MPPED2 and RXRG

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MPPED2	RXRG
Gene Name		metallophosphoesterase domain containing 2	retinoid X receptor, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm
	Molecular Function	Hydrolase Activity Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Steroid Hormone Receptor Activity 9-cis Retinoic Acid Receptor Activity Protein Binding Zinc Ion Binding
	Biological Process	Nervous System Development Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter Peripheral Nervous System Development Heart Development Skeletal Muscle Tissue Development Gene Expression Neuron Differentiation Regulation Of Myelination Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Retinoic Acid Receptor Signaling Pathway Protein Homotetramerization Transmembrane Transport Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Pathways			Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters
Drugs			Adapalene Bexarotene Acitretin Alitretinoin Tretinoin Etretinate
Diseases
GWAS		Chronic kidney disease ( 22479191) Dental caries ( 21940522) Renal function-related traits (eGRFcrea) ( 22797727) Renal function-related traits (sCR) ( 22797727)	AIDS ( 19754311) Menarche (age at onset) ( 21102462) Personality dimensions ( 21368711)
Protein-Protein Interactions		6 interactors: CAGE1 FAM72A NOTCH3 RXRG TRIP13 VAC14	29 interactors: CAMK2B CEBPZ CHGB CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR
Entrez ID		744	6258
HPRD ID		02947	01579
Ensembl ID		ENSG00000066382	ENSG00000143171
Uniprot IDs		Q15777	F1D8Q7 F1T097 P48443
PDB IDs			2GL8
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Glomerular Capillary Formation Biosynthetic Process Female Meiosis I Glomerulus Morphogenesis Transcription, DNA-templated Glomerulus Vasculature Development Notch Receptor Processing RNA Biosynthetic Process Synaptonemal Complex Assembly Oocyte Maturation Synaptonemal Complex Organization Retinoic Acid Receptor Signaling Pathway Male Meiosis I Cellular Response To Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Female Meiotic Division Reciprocal Meiotic Recombination Oocyte Development Cardiovascular System Development Oocyte Differentiation Regulation Of Myelination RNA Metabolic Process Synapsis Regulation Of Lipid Kinase Activity Homologous Chromosome Segregation Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Metabolic Process Male Meiosis Glomerulus Development Cell Differentiation Gene Expression Protein Homotetramerization Cellular Macromolecule Biosynthetic Process Neuron Differentiation Oogenesis Macromolecule Biosynthetic Process Neuron Fate Commitment Meiotic Chromosome Segregation	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Hormone Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Organic Substance Gene Expression Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cholesterol Storage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process
Tagcloud ?			band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr
Tagcloud (Difference) ?			band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr
Tagcloud (Intersection) ?