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UCHL3 and POGK
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
UCHL3
POGK
Gene Name
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
pogo transposable element with KRAB domain
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Extracellular Vesicular Exosome
Nucleus
Molecular Function
Ubiquitin-specific Protease Activity
Protein Binding
Peptidase Activity
Ubiquitin Binding
DNA Binding
Protein Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Pathways
Drugs
Diseases
GWAS
Diabetic retinopathy (
23562823
)
Protein-Protein Interactions
17 interactors:
ATXN7L3
CDH1
HMP19
LONRF1
NEDD8
PJA1
PLA2G2A
POGK
TRIM27
TRIM54
TRIM55
TRIM63
UBC
UBE2S
USP15
USP21
USP28
2 interactors:
APP
UCHL3
Entrez ID
7347
57645
HPRD ID
04367
17872
Ensembl ID
ENSG00000118939
Uniprot IDs
P15374
B4DS22
G3V1P0
Q9P215
PDB IDs
1UCH
1XD3
Enriched GO Terms of Interacting Partners
?
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Catabolic Process
Protein Modification By Small Protein Conjugation
Proteolysis
Histone Deubiquitination
Protein Deubiquitination
Protein Modification By Small Protein Removal
Cellular Protein Modification Process
Protein Ubiquitination
Protein Polyubiquitination
Regulation Of Protein Catabolic Process
Activation Of Anaphase-promoting Complex Activity
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Cellular Protein Metabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Protein Metabolic Process
Regulation Of Proteolysis
Positive Regulation Of Protein Ubiquitination
Protein K11-linked Ubiquitination
Transforming Growth Factor Beta Receptor Signaling Pathway
DNA Damage Checkpoint
Regulation Of Cellular Protein Metabolic Process
Protein K63-linked Ubiquitination
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Ubiquitination
Regulation Of Protein Metabolic Process
Cell Cycle Checkpoint
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Cellular Process
Negative Regulation Of Transferase Activity
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Free Ubiquitin Chain Polymerization
Negative Regulation Of Interleukin-2 Secretion
Histone H2B Conserved C-terminal Lysine Deubiquitination
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Neuron Remodeling
Cellular Copper Ion Homeostasis
Copper Ion Homeostasis
Suckling Behavior
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Mating Behavior
Endoplasmic Reticulum Calcium Ion Homeostasis
Neuron Recognition
RNA Polyadenylation
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Ionotropic Glutamate Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Axon Cargo Transport
Mating
Neuromuscular Junction Development
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Neuron Apoptotic Process
Regulation Of Protein Tyrosine Kinase Activity
Visual Learning
Glutamate Receptor Signaling Pathway
Visual Behavior
Neuron Death
Platelet Degranulation
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuromuscular Process Controlling Balance
Synapse Assembly
MRNA 3'-end Processing
Regulation Of ERBB Signaling Pathway
Associative Learning
Developmental Cell Growth
Regulation Of Synapse Structure Or Activity
Feeding Behavior
Regulation Of Multicellular Organism Growth
Tagcloud
?
attempts
c2
canine
changed
chemokine
depends
eia3
eia4
epo
folding
gstt3
hours
hsp90
hypothetical
introduced
kit
masitinib
mast
neoplastic
pdia3
pro
proliferative
proteome
selenbp1
steroid
tardbp
transcriptionally
transcriptome
tumour
Tagcloud (Difference)
?
attempts
c2
canine
changed
chemokine
depends
eia3
eia4
epo
folding
gstt3
hours
hsp90
hypothetical
introduced
kit
masitinib
mast
neoplastic
pdia3
pro
proliferative
proteome
selenbp1
steroid
tardbp
transcriptionally
transcriptome
tumour
Tagcloud (Intersection)
?