ZNF726 and PFDN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF726	PFDN2
Description		zinc finger protein 726	prefoldin subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Prefoldin Complex Protein-containing Complex Protein Folding Chaperone Complex RPAP3/R2TP/prefoldin-like Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription	Protein Folding Protein Stabilization Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Amyloid Fibril Formation
Pathways		Generic Transcription Pathway	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 28604732)
Interacting Genes		1 interacting genes: PFDN2	10 interacting genes: CEBPA DBI ERBB3 MAP3K3 PFDN1 PFDN4 PKNOX1 UBASH3A VBP1 ZNF726
Entrez ID		730087	5202
HPRD ID			09658
Ensembl ID		ENSG00000213967	ENSG00000143256
Uniprot IDs		A0A8I5GK09 A6NNF4 E9PLI7 F1T0F3	B1AQP2 Q9UHV9
PDB IDs			6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		RPAP3/R2TP/prefoldin-like Complex Negative Regulation Of Amyloid Fibril Formation Prefoldin Complex Regulation Of Amyloid Fibril Formation Protein Folding Chaperone Complex Protein Folding Chaperone Amyloid-beta Binding Unfolded Protein Binding Negative Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Protein Folding	Prefoldin Complex Negative Regulation Of Amyloid Fibril Formation Regulation Of Amyloid Fibril Formation Amyloid-beta Binding Unfolded Protein Binding Protein-containing Complex Regulation Of Supramolecular Fiber Organization Negative Regulation Of Supramolecular Fiber Organization Protein Folding Negative Regulation Of Protein Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Response To Vitamin B2 C/EBP Complex Protein-lipid Complex Negative Regulation Of Protein Lipidation Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Negative Regulation Of Glycine Import Across Plasma Membrane Regulation Of Protein Metabolic Process CHOP-C/EBP Complex Regulation Of Metabolic Process Neuregulin Receptor Activity Negative Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process White Fat Cell Proliferation Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Negative Regulation Of Lipoprotein Metabolic Process ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Dorsal Root Ganglion Development
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