TBC1D3 and CLIC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D3	CLIC3
Description		TBC1 domain family member 3	chloride intracellular channel 3
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane Early Endosome Membrane	Extracellular Region Nucleus Cytoplasm Plasma Membrane Membrane Nuclear Body Extracellular Matrix Monoatomic Ion Channel Complex Chloride Channel Complex Extracellular Exosome
	Molecular Function	GTPase Activator Activity	Chloride Channel Activity Protein Binding Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity
	Biological Process	Regulation Of Cilium Assembly	Monoatomic Ion Transport Chloride Transport Signal Transduction Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Sprouting Angiogenesis
Pathways		TBC/RABGAPs
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Interacting Genes		3 interacting genes: CLIC3 GGA3 ZRANB1	35 interacting genes: AGR2 ALX1 ANKRD23 ANKRD55 APP CIMIP2B DDIT4L DNM1 EFHC2 GLYR1 INCA1 KATNBL1 KRT85 KRTAP13-3 LELP1 MAPK15 MBD3L1 MECOM MIA3 MSX2 POT1 PROSER2 SCML4 SPMIP4 SPMIP6 STMN3 TBC1D3 TBC1D3C TBC1D3K TEPSIN TLE5 VPS4A ZBTB42 ZC2HC1C ZNF620
Entrez ID		729873	9022
HPRD ID		19677	05941
Ensembl ID		ENSG00000274611	ENSG00000169583
Uniprot IDs		Q6IPX1 Q8IZP1	O95833
PDB IDs			3FY7 3KJY
Enriched GO Terms of Interacting Partners?		Protein-disulfide Reductase (glutathione) Activity Positive Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process In The Vacuole Protein K33-linked Deubiquitination Protein K29-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
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