TTK and CTD

Number of citations of the paper that reports this interaction (PMID 9311822)
11

Data Source:
BioGRID (enzymatic study)

		TTK	CTD
Gene Name		TTK protein kinase	Coats disease
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Spindle Organization Mitotic Spindle Organization Mitotic Spindle Assembly Checkpoint Positive Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Chromosome Separation
Pathways
Drugs
Diseases
GWAS			Schizophrenia ( 23212062)
Protein-Protein Interactions		11 interactors: APP AZU1 CASC5 CDCA8 CDK2 CTD MAPK6 RPS6KA1 TP53 TUBB TUBB1	13 interactors: CCNC CCNH CCNT1 CDK7 CDK8 CDK9 CPSF1 GTF2H1 MNAT1 POLR2A TBP TTK WAC
Entrez ID		7272	1283
HPRD ID		04973
Ensembl ID		ENSG00000112742
Uniprot IDs		P33981
PDB IDs		2X9E 2ZMC 2ZMD 3CEK 3DBQ 3GFW 3H9F 3HMN 3HMO 3HMP 3VQU 3W1F 4B94 4BHZ 4BI0 4BI1 4BI2 4H7X 4H7Y
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Mitotic Cell Cycle Microtubule-based Process Negative Regulation Of Hydrolase Activity Cell Division Microtubule Cytoskeleton Organization Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Immune Response Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Catalytic Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Neuron Apoptotic Process Positive Regulation Of Cellular Biosynthetic Process Mitotic Nuclear Division Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Neuron Death Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Fractalkine Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Spindle Assembly Regulation Of Mitotic Cell Cycle Chromosome Organization Cellular Component Assembly Protein Complex Assembly Response To Oxidative Stress Blood Coagulation Hemostasis Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Organelle Organization Regulation Of Cell Cycle Arrest Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Cytoskeleton Organization Negative Regulation Of Macromitophagy Synaptic Growth At Neuromuscular Junction Positive Regulation Of Hepatic Stellate Cell Activation Oligodendrocyte Apoptotic Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Regulation Of Viral Transcription Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Process DNA-templated Transcription, Termination Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression 7-methylguanosine RNA Capping Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Viral Process Regulation Of Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Negative Regulation Of Gene Expression, Epigenetic RNA Metabolic Process Nucleotide-excision Repair Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression, Epigenetic Protein Phosphorylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To DNA Damage Stimulus MRNA Metabolic Process Regulation Of Protein Metabolic Process Nitrogen Compound Metabolic Process RNA Processing
Tagcloud ?		amongst brdu ca centrosome conversely discerning downregulated duplication explored hcc1954 incorporation instability kaplan knockdown manipulation mcf10a mdm2 meier microarray modulators novelty plot pursued resource sfrp1 sgol1 subtype tumorigenic upregulated	ana anas antinuclear assayed awaited connective discordant discrimination dsdna elisa elisas erythematosus fana gives immunosorbent jo labor lupus mana mesacup personnel rnp sera ss ssdna subjective suitable trained uses
Tagcloud (Difference) ?		amongst brdu ca centrosome conversely discerning downregulated duplication explored hcc1954 incorporation instability kaplan knockdown manipulation mcf10a mdm2 meier microarray modulators novelty plot pursued resource sfrp1 sgol1 subtype tumorigenic upregulated	ana anas antinuclear assayed awaited connective discordant discrimination dsdna elisa elisas erythematosus fana gives immunosorbent jo labor lupus mana mesacup personnel rnp sera ss ssdna subjective suitable trained uses
Tagcloud (Intersection) ?