TSN and CFC1

		TSN	CFC1
Description		translin	cryptic, EGF-CFC family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Endoribonuclease Complex	Extracellular Region Plasma Membrane Cell Surface Membrane Side Of Membrane
	Molecular Function	Nucleic Acid Binding DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Nuclease Activity Endonuclease Activity Protein Binding Hydrolase Activity Identical Protein Binding Sequence-specific DNA Binding	Nodal Binding Activin Receptor Binding
	Biological Process	RNA Metabolic Process SiRNA Processing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing	Blood Vessel Development Signal Transduction Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway
Pathways		Small interfering RNA (siRNA) biogenesis	Signaling by NODAL Regulation of signaling by NODAL
Drugs
Diseases			Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS		Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration ( 29346644) Erectile dysfunction and prostate cancer treatment ( 20932654) Food antigen IgG levels ( 24962563) Hepcidin/ferritin ratio ( 27846281) Major depressive disorder x sex interaction ( 34099189) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Smoking status (ever vs never smokers) ( 30643258) Waist circumference ( 34074324)
Interacting Genes		17 interacting genes: CEBPA DVL3 FXR1 GIT2 GORASP2 HOXC4 LNX1 MORF4L2 NTAQ1 PICK1 PPP1R15A SDCBP SIN3A TSNAX UBE2I UBE2K ZBTB18
Entrez ID		7247	55997
HPRD ID		08993	05548
Ensembl ID		ENSG00000211460	ENSG00000136698
Uniprot IDs		B3KRM8 Q15631	A0A087WWV2 A0A087WX98 P0CG37
PDB IDs		1J1J 3PJA 3QB5 4WYV
Enriched GO Terms of Interacting Partners?
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