TPP2 and EHHADH

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TPP2	EHHADH
Gene Name		tripeptidyl peptidase II	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Mitochondrion Peroxisome Cytosol
	Molecular Function	Endopeptidase Activity Aminopeptidase Activity Serine-type Endopeptidase Activity Tripeptidyl-peptidase Activity	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Receptor Binding Enzyme Binding Coenzyme Binding
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Proteolysis	Internal Protein Amino Acid Acetylation Fatty Acid Beta-oxidation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs			NADH
Diseases
GWAS			Cognitive performance ( 19734545) Major depressive disorder ( 21042317)
Protein-Protein Interactions		3 interactors: EHHADH POLB PPP1R16A	27 interactors: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9
Entrez ID		7174	1962
HPRD ID		01834	06125
Ensembl ID		ENSG00000134900	ENSG00000113790
Uniprot IDs		P29144 Q5VZU9	Q08426 Q9NY65
PDB IDs
Enriched GO Terms of Interacting Partners?		Base-excision Repair, Gap-filling Pyrimidine Dimer Repair Fatty Acid Beta-oxidation Neuron Apoptotic Process Base-excision Repair Neuron Death Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process	Cellular Component Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Complex Assembly Organelle Organization Negative Regulation Of Microtubule Depolymerization Intraciliary Transport Cytoskeleton Organization Purine Nucleotide Catabolic Process Platelet Aggregation Protein Oligomerization Microtubule-based Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Cysteine Biosynthetic Process From Serine Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport Homocysteine Catabolic Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Cysteine Biosynthetic Process Via Cystathionine Response To Stimulus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Serine Family Amino Acid Metabolic Process Defense Response Retina Homeostasis Protein Homooligomerization Signal Transduction Regulation Of Intracellular Cholesterol Transport Negative Regulation Of Interleukin-2 Secretion Transsulfuration Protein Ubiquitination Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Viral Process Nucleotide Catabolic Process Protein Modification By Small Protein Conjugation Depurination Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Adherens Junction Organization Signaling Immune System Process L-serine Catabolic Process Inositol Trisphosphate Biosynthetic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Response To Stress Negative Regulation Of Protein Complex Disassembly Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Communication Cellular Response To Stimulus Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Tagcloud ?			1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Difference) ?			1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Intersection) ?