C1QB and C1R

Number of citations of the paper that reports this interaction (PMID 1370572)
1

Data Source:
HPRD (in vivo)

		C1QB	C1R
Gene Name		complement component 1, q subcomponent, B chain	complement component 1, r subcomponent
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Complement Component C1 Complex Extracellular Vesicular Exosome Blood Microparticle	Extracellular Region Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Binding Protein Homodimerization Activity	Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Serine-type Peptidase Activity
	Biological Process	Complement Activation Complement Activation, Classical Pathway Innate Immune Response Inner Ear Development	Proteolysis Immune Response Complement Activation Complement Activation, Classical Pathway Innate Immune Response
Pathways		Classical antibody-mediated complement activation Creation of C4 and C2 activators Complement cascade Initial triggering of complement Innate Immune System	Classical antibody-mediated complement activation Creation of C4 and C2 activators Complement cascade Initial triggering of complement Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: C1QA C1QC C1R DEFA1 EDA2R HRG IL32 MYOC PTX3 RELA	7 interactors: C1QA C1QB C1S CSNK2A1 EP300 PCK1 SERPING1
Entrez ID		713	715
HPRD ID		00394	01954
Ensembl ID		ENSG00000173369
Uniprot IDs		P02746	P00736
PDB IDs		1PK6 2JG8 2JG9 2WNU 2WNV	1APQ 1GPZ 1MD7 1MD8 2QY0
Enriched GO Terms of Interacting Partners?		Defense Response Immune Response Innate Immune Response Response To Fungus Humoral Immune Response Positive Regulation Of Immune Response Immune System Process Response To Stress Regulation Of Immune Response Positive Regulation Of Immune System Process Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Response To Stimulus Protein Activation Cascade Positive Regulation Of Focal Adhesion Assembly Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Positive Regulation Of Adherens Junction Organization Defense Response To Fungus Regulation Of Immune System Process Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Response To Other Organism Leukocyte Mediated Immunity Adaptive Immune Response Response To Biotic Stimulus Regulation Of Focal Adhesion Assembly Positive Regulation Of Cell-matrix Adhesion Regulation Of Cell Junction Assembly ERBB2-ERBB3 Signaling Pathway Skeletal Muscle Hypertrophy Acetaldehyde Metabolic Process Cellular Response To Tumor Necrosis Factor ERBB2 Signaling Pathway Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Positive Regulation Of Schwann Cell Differentiation Heme Export Positive Regulation Of Blood Vessel Remodeling Negative Regulation Of Exo-alpha-sialidase Activity Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Schwann Cell Differentiation Negative Regulation Of Lamellipodium Assembly Response To Tumor Necrosis Factor Negative Regulation Of Endothelial Cell Chemotaxis Response To Cobalamin Defense Response To Virus Regulation Of Locomotion	Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Protein Activation Cascade Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Adaptive Immune Response Innate Immune Response Immune Response Defense Response Positive Regulation Of Immune Response Protein Metabolic Process Regulation Of Immune Response Positive Regulation Of Immune System Process Immune System Process Regulation Of Immune System Process Histone H2B Acetylation Glycerol Biosynthetic Process From Pyruvate Internal Protein Amino Acid Acetylation Negative Regulation Of Complement Activation, Lectin Pathway Response To Stimulus Protein Acetylation N-terminal Peptidyl-lysine Acetylation Glycerol Biosynthetic Process Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Positive Regulation By Host Of Viral Transcription Rhythmic Process N-terminal Protein Amino Acid Acetylation Negative Regulation Of Complement Activation Negative Regulation Of Proteolysis Blood Coagulation, Intrinsic Pathway Negative Regulation Of Protein Processing Oxaloacetate Metabolic Process Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Androgen Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification
Tagcloud ?		antioxidative atf3 atf4 atf5 axonal believe c1qa c1qc c57bl chac1 chop concurrently crush defense egr1 ganglion glaucoma hmox1 ocular onc optic retinal retinas rgc seq sham srxn1 transcriptome trb3	a2 allogeneic autologous candidates cold ctl ctls demonstrating encoded epitopes gastric her2 hla ic50 immunodominance immunotherapy implicate lymphocyte lysed naturally neu processed recognized repetitive restricted sensitize sw626 tal transfected
Tagcloud (Difference) ?		antioxidative atf3 atf4 atf5 axonal believe c1qa c1qc c57bl chac1 chop concurrently crush defense egr1 ganglion glaucoma hmox1 ocular onc optic retinal retinas rgc seq sham srxn1 transcriptome trb3	a2 allogeneic autologous candidates cold ctl ctls demonstrating encoded epitopes gastric her2 hla ic50 immunodominance immunotherapy implicate lymphocyte lysed naturally neu processed recognized repetitive restricted sensitize sw626 tal transfected
Tagcloud (Intersection) ?