SERPINA7 and SLC16A2

Number of citations of the paper that reports this interaction (PMID 12871948)
76

Data Source:
HPRD (in vitro, in vivo)

		SERPINA7	SLC16A2
Gene Name		serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	solute carrier family 16, member 2 (thyroid hormone transporter)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome	Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Hormone Binding	Transporter Activity Monocarboxylic Acid Transmembrane Transporter Activity Symporter Activity Thyroid Hormone Transmembrane Transporter Activity
	Biological Process	Aging Post-embryonic Development Negative Regulation Of Endopeptidase Activity Response To Vitamin A Response To Prostaglandin E Response To Drug Response To Peptide Hormone Response To Corticosterone Thyroid Hormone Transport	Transport Monocarboxylic Acid Transport Ion Transmembrane Transport Thyroid Hormone Transport
Pathways
Drugs			Pyruvic acid
Diseases
GWAS
Protein-Protein Interactions		1 interactors: SLC16A2	2 interactors: SERPINA7 THRA
Entrez ID		6906	6567
HPRD ID		02438	02106
Ensembl ID		ENSG00000123561	ENSG00000147100
Uniprot IDs		P05543	P36021
PDB IDs		2CEO 2RIV 2RIW 2XN3 2XN5 2XN6 2XN7
Enriched GO Terms of Interacting Partners?		Thyroid Hormone Transport Hormone Transport Monocarboxylic Acid Transport Regulation Of Hormone Levels Carboxylic Acid Transport Organic Acid Transport Anion Transmembrane Transport Organic Anion Transport	Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Female Receptivity Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Response To Steroid Hormone Thyroid Hormone Transport Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Female Courtship Behavior Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Female Receptivity Female Mating Behavior Response To Lipid Type I Pneumocyte Differentiation Response To Organic Cyclic Compound Cytoplasmic Sequestering Of Transcription Factor Response To Prostaglandin E Response To Hormone Cytoplasmic Sequestering Of Protein Cartilage Condensation Regulation Of DNA-templated Transcription, Initiation Thyroid Gland Development Response To Vitamin A Positive Regulation Of Myotube Differentiation Mating Behavior Response To Corticosterone Regulation Of Myeloid Cell Apoptotic Process Response To Mineralocorticoid Negative Regulation Of Transcription Factor Import Into Nucleus Mating Response To Cold Regulation Of Lipid Catabolic Process Regulation Of Myotube Differentiation Lung Epithelial Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Negative Regulation Of Protein Import Into Nucleus Response To Fatty Acid Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Hormone Transport Negative Regulation Of Cellular Metabolic Process Regulation Of Striated Muscle Cell Differentiation Erythrocyte Differentiation Steroid Hormone Mediated Signaling Pathway Response To Vitamin Erythrocyte Homeostasis Negative Regulation Of Intracellular Transport
Tagcloud ?		22q11 agps arrays bioinformatic cnvs dgkb duplication extreme gwas hoxd4 novo nrk osbpl6 pde11a plates plekha3 prenatal prkra rodents segregation shox snp stature tall tnfrsf11b uncovered upd14 upd7	cga deiodinase dio2 hypothalamic hypothalamus intra intraperitoneal ko littermates mct mct8 nbr neuromedin paracrine pituitary releasing slight t3 t4 thrb thyroid thyroidal thyrotropin thyroxine trh trhr triiodothyronine tsh tshb
Tagcloud (Difference) ?		22q11 agps arrays bioinformatic cnvs dgkb duplication extreme gwas hoxd4 novo nrk osbpl6 pde11a plates plekha3 prenatal prkra rodents segregation shox snp stature tall tnfrsf11b uncovered upd14 upd7	cga deiodinase dio2 hypothalamic hypothalamus intra intraperitoneal ko littermates mct mct8 nbr neuromedin paracrine pituitary releasing slight t3 t4 thrb thyroid thyroidal thyrotropin thyroxine trh trhr triiodothyronine tsh tshb
Tagcloud (Intersection) ?