TARBP1 and SDHB

		TARBP1	SDHB
Description		tRNA guanosine 2 -O-methyltransferase TARBP1	succinate dehydrogenase complex iron sulfur subunit B
Image
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex II (succinate Dehydrogenase)
	Molecular Function	TRNA Binding RNA Binding Methyltransferase Activity RNA Methyltransferase Activity TRNA (guanine) Methyltransferase Activity Transferase Activity TRNA (guanine(18)-2'-O)-methyltransferase Activity	Protein Binding Succinate Dehydrogenase (quinone) Activity Electron Transfer Activity Oxidoreductase Activity Metal Ion Binding Ubiquinone Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II RNA Processing TRNA Processing TRNA Methylation Methylation	Tricarboxylic Acid Cycle Succinate Metabolic Process Mitochondrial Electron Transport, Succinate To Ubiquinone Aerobic Respiration Respiratory Electron Transport Chain Proton Motive Force-driven Mitochondrial ATP Synthesis
Pathways			Respiratory electron transport Citric acid cycle (TCA cycle) Maturation of TCA enzymes and regulation of TCA cycle
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Cognitive test performance ( 17903297) Psoriasis ( 25854761) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)	A body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Hip circumference adjusted for BMI ( 34021172) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		3 interacting genes: ERG RNF10 SREK1	8 interacting genes: ABCA1 CARTPT GEM MSRA PIK3R5 SPRY2 TMEM132D XRN1
Entrez ID		6894	6390
HPRD ID		05445	01707
Ensembl ID		ENSG00000059588	ENSG00000117118
Uniprot IDs		Q13395	A0AAQ5BHD9 P21912
PDB IDs		2HA8	7KCL 7KCM 7KLU 7KLV 8GS8
Enriched GO Terms of Interacting Partners?		Mitochondrial Electron Transport, Succinate To Ubiquinone Respiratory Chain Complex II (succinate Dehydrogenase) Succinate Dehydrogenase (quinone) Activity 3 Iron, 4 Sulfur Cluster Binding Succinate Metabolic Process Ubiquinone Binding Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Disulfide Oxidoreductase Activity Insulin Processing Thiol Oxidase Activity	Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Rho Protein Signal Transduction
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?