SDHB

Gene Name		succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Carrier Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Height ( 20189936)
Protein-protein Interactions		5 interactors: ABCA1 GEM PIK3R5 SPRY2 XRN1
Entrez ID		6390
HPRD ID		01707
Ensembl ID		ENSG00000117118
Uniprot IDs		P21912
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Kinase B Signaling Regulation Of Protein Kinase B Signaling Interleukin-1 Beta Secretion Apolipoprotein A-I-mediated Signaling Pathway Interleukin-1 Secretion Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Nuclear MRNA Surveillance Cell Surface Receptor Signaling Pathway Regulation Of MAP Kinase Activity Negative Regulation Of Cholesterol Storage Lung Growth High-density Lipoprotein Particle Assembly RNA Surveillance Establishment Of Organelle Localization Intracellular Cholesterol Transport Intracellular Sterol Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Histone MRNA Catabolic Process Phospholipid Homeostasis Platelet Dense Granule Organization Regulation Of Phosphorus Metabolic Process RRNA Catabolic Process Phospholipid Efflux Phagocytosis, Engulfment Bud Elongation Involved In Lung Branching Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Organelle Localization Cellular Response To Cholesterol Negative Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of MAPK Cascade Reverse Cholesterol Transport Response To Laminar Fluid Shear Stress Membrane Invagination Regulation Of Intracellular Signal Transduction Protein-lipid Complex Assembly Response To Lipoprotein Particle Positive Regulation Of Protein Kinase Activity Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Lipid Storage Positive Regulation Of Kinase Activity Negative Regulation Of Ras GTPase Activity Positive Regulation Of Cholesterol Transport Histone MRNA Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cholesterol Efflux Phosphatidylinositol 3-kinase Signaling
Tagcloud ?		alters anatomical bacteremia bacterium colonization colonizing competitors divergent fitness frda fumc genitourinary gluconeogenesis glycolysis mirabilis niche nutritional occupying pentose pfka pgi polymicrobial proteus pyka requirements tca tpia uncomplicated uropathogenic