COPG2 and COPZ1

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, biochemical)
HPRD (two hybrid)

		COPG2	COPZ1
Description		coat protein complex I subunit gamma 2	coat protein complex I subunit zeta 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Growth Cone COPI-coated Vesicle Membrane Cytoplasmic Vesicle Bounding Membrane Of Organelle	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Organelle Transport Along Microtubule	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		A body shape index ( 34021172) Pancreatic cancer ( 25086665) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Chronotype ( 30696823) Hematocrit ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 22139419 24026423 27863252 32888494) Meat-related diet ( 32066663) Platelet count ( 23263863 32888494 29403010) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 27863252 32888494) Red cell distribution width ( 27863252 32888494) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10	6 interacting genes: APP COPG1 COPG2 TMED10 TMED9 UGT1A1
Entrez ID		26958	22818
HPRD ID		05074	16738
Ensembl ID		ENSG00000158623	ENSG00000111481
Uniprot IDs		A0A140VK12 Q9UBF2	P61923
PDB IDs			2HF6 5MC7
Enriched GO Terms of Interacting Partners?		COPI Vesicle Coat COPI-coated Vesicle Membrane Transport Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Intra-Golgi Vesicle-mediated Transport Golgi Membrane COPI-coated Vesicle Intracellular Protein Transport Endoplasmic Reticulum Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Establishment Of Localization In Cell Intracellular Protein Localization Cytoplasmic Vesicle Golgi Apparatus Membrane Coat Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Localization Protein Localization To Golgi Apparatus Structural Molecule Activity Cis-Golgi Network MHC Class Ib Protein Complex Assembly Peptide Antigen Stabilization Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Cerebellar Purkinje Cell Layer Maturation Phospholipase D Activator Activity Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs G Protein-coupled Receptor Complex Tapasin-ERp57 Complex Adult Locomotory Behavior Secretory Granule Membrane Conditioned Taste Aversion Sensitization TAP2 Binding TAP Complex Binding Prostaglandin-E Synthase Activity Endoplasmic Reticulum Membrane Habituation Operant Conditioning Unfolded Protein Binding TAP1 Binding	Endoplasmic Reticulum-Golgi Intermediate Compartment Transport Vesicle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Golgi Vesicle Transport COPI Coating Of Golgi Vesicle Endoplasmic Reticulum Membrane Intracellular Transport Vesicle-mediated Transport COPI-coated Vesicle COPI Vesicle Coat Trans-Golgi Network Transport Vesicle Intracellular Protein Transport COPI-coated Vesicle Membrane Golgi Apparatus Transport Along Microtubule Golgi Membrane Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Transport Membrane Coat Intra-Golgi Vesicle-mediated Transport Vesicle Coating COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Syntaxin Binding Regulation Of Amyloid Precursor Protein Catabolic Process Protein Transport Microtubule-based Movement Secretion By Cell Positive Regulation Of Interleukin-1 Production Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Organelle Transport Along Microtubule Establishment Of Protein Localization Secretion Acetylcholine Receptor Activator Activity Regulation Of Interleukin-1 Production Lipoprotein Particle Positive Regulation Of Protein Import Golgi Organization
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