SUPV3L1 and ADAP1

Number of citations of the paper that reports this interaction (PubMedID 16176273)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SUPV3L1	ADAP1
Description		Suv3 like RNA helicase	ArfGAP with dual PH domains 1
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Mitochondrial Degradosome	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity 3'-5' RNA Helicase Activity Identical Protein Binding Protein Homodimerization Activity	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Mitochondrial RNA Catabolic Process Mitochondrial MRNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial RNA 3'-end Processing DNA Recombination RNA Catabolic Process Mitochondrion Organization Positive Regulation Of Cell Growth Mitochondrial NcRNA Surveillance Mitochondrial MRNA Surveillance Negative Regulation Of Apoptotic Process Mitochondrial RNA Surveillance	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity
Pathways		Mitochondrial RNA degradation	Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Facial morphology ( 31763980) Glycemic traits (pregnancy) ( 23903356) Immune reponse to smallpox (secreted IL-1beta) ( 22610502)	Apolipoprotein A1 levels ( 32203549) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		7 interacting genes: ADAP1 DSCAM EIF4ENIF1 LZTS2 MAGEB6 RBFOX2 RNF10	24 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1
Entrez ID		6832	11033
HPRD ID		05493	09733
Ensembl ID		ENSG00000156502	ENSG00000105963
Uniprot IDs		B7Z611 Q8IYB8	A0A087WTN6 A8K3A2 B4DUZ7 O75689
PDB IDs		3RC3 3RC8 7W1R	3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?			Diacylglycerol-dependent Serine/threonine Kinase Activity Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Phosphorylation Phosphorylation Insulin Receptor Substrate Binding Kinase Activity Intracellular Signal Transduction Protein Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Metabolic Process PAR Polarity Complex Positive Regulation Of Protein Localization Positive Regulation Of Signal Transduction Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Response To Peptide Hormone Positive Regulation Of Cellular Component Biogenesis ATP Binding Positive Regulation Of Cell Communication Regulation Of Signal Transduction Nucleus Positive Regulation Of Signaling Regulation Of Apoptotic Process Microtubule-based Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Cellular Component Organization Beta-catenin Destruction Complex Response To Phorbol 13-acetate 12-myristate Regulation Of Programmed Cell Death Positive Regulation Of Cell Projection Organization Regulation Of Metabolic Process Regulation Of Autophagy Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Response To Hormone Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Localization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Ketone Positive Regulation Of Protein Localization To Membrane Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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