ELOVL4 and SERF1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ELOVL4	SERF1A
Description		ELOVL fatty acid elongase 4	small EDRK-rich factor 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding G Protein-coupled Photoreceptor Activity Fatty Acid Elongase Activity Transferase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Detection Of Visible Light Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Nervous System Development Protein Destabilization Amyloid Fibril Formation
Pathways		Synthesis of very long-chain fatty acyl-CoAs
Drugs		Omega-3-carboxylic acids
Diseases		Stargardt disease (STGD); Fundus flavimaculatus
GWAS		Aging ( 22773346) Body mass index ( 23669352) Chronic obstructive pulmonary disease ( 28166215) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Macular thickness ( 30535121) Partial epilepsies ( 20522523) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		106 interacting genes: ADGRE2 ANKRD46 APOL2 APOL3 ARLN ATP13A1 BCL2L1 BET1 BIK BNIP1 BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD70 CDIPT CLCA4 CLDND2 CMTM3 CMTM5 CMTM7 COL4A5 CYB5R3 CYP4F2 EMC6 ERG28 FA2H FAM177A1 FAM3C FAXDC2 FDFT1 FKBP8 FXYD6 GIMAP1 GIMAP5 GOSR2 GPR37L1 GYPA HMOX1 HMOX2 HSD3B7 IER3IP1 INSIG2 ITGAM JAGN1 LEPROTL1 LHFPL5 LPAR3 LY6D MALL MMP14 NINJ2 ORMDL2 ORMDL3 PEX16 PKMYT1 PLLP PLN PLP1 PTPN1 RAB18 RTP2 SEC22A SEC22B SERF1A SERF1B SERP2 SFT2D2 SLC30A3 SLC30A8 SMCO4 SMIM1 SNORC STX3 STX8 SYNDIG1 TECR TF TMEM11 TMEM128 TMEM19 TMEM203 TMEM218 TMEM222 TMEM242 TMEM243 TMEM254 TMEM42 TMEM44 TRARG1 TREX1 TSNARE1 UBE2J1 UBIAD1 UNC50 VAMP1 VAMP3 VAMP4 VAMP5 VAPB VMA12 YIF1A YIPF6 ZDHHC21 ZFPL1	15 interacting genes: ABHD16A APP AQP6 CERS4 CRB3 ELOVL4 ELOVL7 GPR152 LRRK2 PIK3R3 REEP4 RNASEK TIMMDC1 TMEM14B TMX2
Entrez ID		6785	8293
HPRD ID		05697	04308
Ensembl ID		ENSG00000118402	ENSG00000172058
Uniprot IDs		Q9GZR5	O75920
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Endomembrane System Membrane Fusion Organelle Fusion Organelle Membrane Fusion Vesicle-mediated Transport Golgi Vesicle Transport Establishment Of Protein Localization Vesicle Fusion Protein Binding Membrane Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle Organization Cellular Localization Sterol Biosynthetic Process Establishment Of Protein Localization To Membrane Golgi Membrane Steroid Biosynthetic Process Mitochondrial Membrane Membrane Docking Structural Constituent Of Myelin Sheath Intracellular Transport Endoplasmic Reticulum Organization Heme Oxidation Heme Oxygenase (decyclizing) Activity Transport Vesicle SNARE Complex Assembly Lipid Biosynthetic Process Organelle Localization By Membrane Tethering Sterol Metabolic Process Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Golgi Apparatus Insulin Metabolic Process Inorganic Ion Homeostasis Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Establishment Of Protein Localization To Plasma Membrane Establishment Of Localization In Cell Intracellular Protein Localization Intracellular Chemical Homeostasis Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Menaquinone Metabolic Process Negative Regulation Of Sphingolipid Biosynthetic Process Vesicle Docking Steroid Metabolic Process	Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Mitochondrial Membrane Membrane Cellular Response To Manganese Ion Fatty Acid Elongation, Saturated Fatty Acid Fatty Acid Derivative Metabolic Process Response To Manganese Ion Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Sphingolipid Biosynthetic Process Golgi-associated Vesicle Cellular Response To Catecholamine Stimulus Response To Catecholamine Long-chain Fatty-acyl-CoA Biosynthetic Process Endoplasmic Reticulum Endoplasmic Reticulum Membrane Long-chain Fatty-acyl-CoA Metabolic Process Amide Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Sphingolipid Metabolic Process Regulation Of Lysosomal Lumen PH Very Long-chain Fatty Acid Metabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Membrane Lipid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Modulation Of Excitatory Postsynaptic Potential Nitrate Transmembrane Transporter Activity Organophosphate Metabolic Process Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Lipid Biosynthetic Process Fatty Acid Derivative Biosynthetic Process Endoplasmic Reticulum Organization Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Lipid Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?