SRP9 and SRP14

Number of citations of the paper that reports this interaction (PMID 11089964)
45

Data Source:
HPRD (in vitro)

		SRP9	SRP14
Gene Name		signal recognition particle 9kDa	signal recognition particle 14kDa (homologous Alu RNA binding protein)
Image
Gene Ontology Annotations	Cellular Component	Signal Recognition Particle Receptor Complex Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Extracellular Vesicular Exosome	Nucleus Nucleolus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Intercellular Bridge Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Signal Recognition Particle Binding 7S RNA Binding	RNA Binding Protein Binding 7S RNA Binding Endoplasmic Reticulum Signal Peptide Binding Poly(A) RNA Binding
	Biological Process	Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Cellular Protein Metabolic Process Negative Regulation Of Translational Elongation	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Response To Drug Cellular Protein Metabolic Process Protein Targeting To ER
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane	Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS			Ewing sarcoma ( 22327514) Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: IL7R SRP14	4 interactors: CALM1 IL7R NSFL1C SRP9
Entrez ID		6726	6727
HPRD ID		02830	02831
Ensembl ID		ENSG00000143742	ENSG00000140319
Uniprot IDs		P49458	P37108
PDB IDs		1E8O 1E8S 1RY1	1E8O 1E8S 1RY1
Enriched GO Terms of Interacting Partners?		Interleukin-7-mediated Signaling Pathway Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of T Cell Mediated Immunity Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Adaptive Immune Response B Cell Proliferation Immunoglobulin Production Regulation Of DNA Recombination Positive Regulation Of T Cell Differentiation Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Lymphocyte Differentiation SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Leukocyte Mediated Cytotoxicity Lymphocyte Proliferation Mononuclear Cell Proliferation Leukocyte Proliferation Regulation Of T Cell Differentiation Protein Localization To Endoplasmic Reticulum Negative Regulation Of Immune Response Regulation Of Cell Size	Membrane Organization Interleukin-7-mediated Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of Translational Elongation Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of T Cell Mediated Cytotoxicity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Nuclear Envelope Reassembly Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of T Cell Mediated Immunity Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Cell Activation Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Adaptive Immune Response Response To Mineralocorticoid Regulation Of Nitric-oxide Synthase Activity
Tagcloud ?		6j ampa antecedent c57bl conveys css1 currents epilepsy febrile forward fs genetically glua1 hippocampal hyperthermia interpretation lobe mapped mesial mtle parental qtl1 rs12403575 seizure seizures snp substitution susceptibility trait
Tagcloud (Difference) ?		6j ampa antecedent c57bl conveys css1 currents epilepsy febrile forward fs genetically glua1 hippocampal hyperthermia interpretation lobe mapped mesial mtle parental qtl1 rs12403575 seizure seizures snp substitution susceptibility trait
Tagcloud (Intersection) ?