SRP9 and SRP14

Number of citations of the paper that reports this interaction (PubMedID 2153922)
32

Data Source:
HPRD (in vitro)

		SRP9	SRP14
Description		signal recognition particle 9	signal recognition particle 14
Image
GO Annotations	Cellular Component	Cytoplasm Signal Recognition Particle Receptor Complex Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle Ribonucleoprotein Complex	Extracellular Region Nucleus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Secretory Granule Lumen Signal Recognition Particle Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex
	Molecular Function	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding	RNA Binding Protein Binding 7S RNA Binding Endoplasmic Reticulum Signal Peptide Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane Negative Regulation Of Translational Elongation	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Protein Targeting To ER
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Neutrophil degranulation
Drugs			Artenimol
Diseases
GWAS		Antisaccade task score ( 31596458) Endometrial cancer ( 30093612) Lymphocyte count ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 27067015) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 27863252 32888494) Red cell distribution width ( 32888494)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Ewing sarcoma ( 22327514) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alanine transaminase) ( 33972514) Obesity-related traits ( 23251661) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		5 interacting genes: ACTN2 CEBPA IL7R SRP14 UBC	10 interacting genes: CALM1 CEBPA EAF1 FOXP1 IL7R NSFL1C PTEN SPANXN2 SRP9 UBC
Entrez ID		6726	6727
HPRD ID		02830	02831
Ensembl ID		ENSG00000143742	ENSG00000140319
Uniprot IDs		P49458	P37108
PDB IDs		1E8O 1E8S 1RY1 4UYJ 4UYK 5AOX 7NFX	1E8O 1E8S 1RY1 4UYJ 4UYK 5AOX 7NFX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endocytic Recycling Titin Z Domain Binding Regulation Of Cellular Component Size Structural Constituent Of Postsynaptic Actin Cytoskeleton Protein Domain Specific Binding Cell Development Channel Activator Activity Microspike Assembly Phospholipase C-activating Angiotensin-activated Signaling Pathway Actin Filament Uncapping FATZ Binding LIM Domain Binding CHOP-C/EBP Complex Response To Phenylpropanoid RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 White Fat Cell Proliferation C/EBP Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Fat Cell Proliferation Interleukin-7-mediated Signaling Pathway Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7 Receptor Activity Signal Recognition Particle, Endoplasmic Reticulum Targeting Endoplasmic Reticulum Signal Peptide Binding 7S RNA Binding Signal Recognition Particle	Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Receptor Signaling Pathway Via JAK-STAT Nucleoplasm Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Mononuclear Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Regulation Of Cell Size Regulation Of Lymphocyte Apoptotic Process Negative Regulation Of Lymphocyte Apoptotic Process Negative Regulation Of Leukocyte Apoptotic Process Interleukin-7 Receptor Activity Negative Regulation Of Synaptic Vesicle Clustering Membrane Assembly Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Organ Growth Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Interleukin-21 Production VCP-NSFL1C Complex Negative Regulation Of Protein Localization To Centrosome Regulation Of Cell Development
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