SPTB and CSRP3

Number of citations of the paper that reports this interaction (PMID 10751147)
17

Data Source:
HPRD (in vivo, in vitro)

		SPTB	CSRP3
Gene Name		spectrin, beta, erythrocytic	cysteine and glycine-rich protein 3 (cardiac LIM protein)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Spectrin Cell Surface Spectrin-associated Cytoskeleton Actin Cytoskeleton Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Protein Complex	Nucleus Cytoskeleton Z Disc
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Ankyrin Binding Protein Heterodimerization Activity Actin Filament Binding	Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Telethonin Binding Actinin Binding
	Biological Process	Porphyrin-containing Compound Biosynthetic Process Plasma Membrane Organization Axon Guidance Hemopoiesis Actin Filament Capping	Regulation Of The Force Of Heart Contraction Cardiac Muscle Hypertrophy Cellular Calcium Ion Homeostasis Skeletal Muscle Tissue Development Protein Localization To Organelle Detection Of Muscle Stretch Positive Regulation Of Transcription From RNA Polymerase II Promoter Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Cardiac Muscle Contraction
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		11 interactors: ADD1 ANK1 AP1G1 CSRP3 DMTN EPB41 MAPT NCAM1 SPTA1 SPTAN1 YWHAQ	8 interactors: ACTN1 HDAC4 LDHD MYF6 MYOD1 MYOG NHLH1 SPTB
Entrez ID		6710	8048
HPRD ID		01686	07525
Ensembl ID		ENSG00000070182	ENSG00000129170
Uniprot IDs		P11277 Q59FP5 Q86TX9	A2TDB8 P50461
PDB IDs		1S35 3EDU 3F57 3KBT 3KBU 3LBX	2O10 2O13
Enriched GO Terms of Interacting Partners?		Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Cytoskeleton Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Protein Complex Disassembly Negative Regulation Of Protein Complex Assembly Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Polymerization Cell Differentiation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cytoskeleton Organization Axonogenesis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Morphogenesis Axon Development Homeostasis Of Number Of Cells Positive Regulation Of Protein Binding Cell Morphogenesis Involved In Neuron Differentiation Cell Development Developmental Process Actin Cytoskeleton Organization Execution Phase Of Apoptosis Neuron Projection Morphogenesis Actin Filament-based Process Regulation Of Cellular Component Organization System Development Cell Morphogenesis Involved In Differentiation Organelle Organization Erythrocyte Differentiation Regulation Of Actin Cytoskeleton Organization Erythrocyte Homeostasis Neuron Projection Development Multicellular Organismal Development Positive Regulation Of Binding Axon Guidance Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Actin Filament-based Process Anatomical Structure Development Anatomical Structure Morphogenesis Myeloid Cell Homeostasis Regulation Of Protein Binding	Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Myotube Differentiation Regulation Of Skeletal Muscle Tissue Development Muscle Cell Fate Commitment Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Regulation Of Striated Muscle Tissue Development Positive Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Positive Regulation Of Myotube Differentiation Regulation Of Myoblast Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Response To Denervation Involved In Regulation Of Muscle Adaptation Positive Regulation Of Muscle Cell Differentiation Response To Inactivity Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Cellular Response To Estradiol Stimulus Skeletal Muscle Fiber Development Positive Regulation Of Transcription, DNA-templated Skeletal Muscle Tissue Regeneration Cellular Response To Estrogen Stimulus Myotube Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Muscle System Process Muscle Organ Development Cell Fate Commitment Regulation Of Cell Development Transcription From RNA Polymerase II Promoter Muscle Fiber Development Striated Muscle Tissue Development Regulation Of Transcription From RNA Polymerase II Promoter Muscle Cell Differentiation Tissue Regeneration Muscle Tissue Development Myotube Differentiation Cell Differentiation Positive Regulation Of Muscle Atrophy Transcription, DNA-templated RNA Biosynthetic Process
Tagcloud ?		ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 ugt1a1	actinin actn3 anabolic bout carp catabolic ck creatine eccentric extensions homozygotes investigates legs mafbx mrf4 murf myf5 myod1 myogenin myostatin nineteen protecting r577x rcan1 rr sarcomere satellite tended xx
Tagcloud (Difference) ?		ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 ugt1a1	actinin actn3 anabolic bout carp catabolic ck creatine eccentric extensions homozygotes investigates legs mafbx mrf4 murf myf5 myod1 myogenin myostatin nineteen protecting r577x rcan1 rr sarcomere satellite tended xx
Tagcloud (Intersection) ?