NOL12 and SAP18

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOL12	SAP18
Gene Name		nucleolar protein 12	Sin3A-associated protein, 18kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus	Histone Deacetylase Complex Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	RRNA Binding Poly(A) RNA Binding	Transcription Corepressor Activity Protein Binding Poly(A) RNA Binding
	Biological Process		Regulation Of Alternative MRNA Splicing, Via Spliceosome Chromatin Organization Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter MRNA Processing RNA Splicing Gene Expression Regulation Of Gene Expression, Epigenetic Positive Regulation Of Apoptotic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP CDK4 CEP70 DVL3 KIAA1191 KRTAP10-7 SAP18 SF3B3 SLC25A38 SOD2 SSX2IP TERF1	11 interactors: HDAC1 IKZF1 INCA1 NOL12 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3
Entrez ID		79159	10284
HPRD ID		17537	04256
Ensembl ID		ENSG00000100101	ENSG00000150459
Uniprot IDs		Q9UGY1	O00422
PDB IDs			2HDE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Drug Response To Hyperoxia Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Regulation Of Mitotic Cell Cycle MRNA Processing Regulation Of Fibroblast Proliferation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cellular Component Assembly Regulation Of Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Organelle Organization Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening Response To Silicon Dioxide Response To Magnetism MRNA Metabolic Process Microtubule-based Transport Telomere Maintenance Via Telomere Shortening Cytoskeleton-dependent Intracellular Transport RNA Processing Transition Metal Ion Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Detection Of Oxygen Collateral Sprouting Axon Midline Choice Point Recognition Non-canonical Wnt Signaling Pathway Via JNK Cascade Age-dependent Response To Oxidative Stress Positive Regulation Of Cell Death Homeostatic Process Intraciliary Transport Involved In Cilium Morphogenesis Response To Selenium Ion Negative Regulation Of Telomere Maintenance Via Telomerase Smooth Endoplasmic Reticulum Calcium Ion Homeostasis	Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Chromatin Organization Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Nitrogen Compound Metabolic Process Histone Deacetylation Protein Deacetylation Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Neutrophil Differentiation Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Negative Regulation Of Protein Localization To Nucleus Regulation Of RNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of Histone Modification Positive Regulation Of Chromatin Silencing Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Tubulin Deacetylation Error-prone Translesion Synthesis Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Metabolic Process Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Tagcloud ?			agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?			agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?