NOL12 and SAP18

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOL12	SAP18
Description		nucleolar protein 12	Sin3A associated protein 18
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Histone Deacetylase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding RRNA Binding Identical Protein Binding	Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process		Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	HDACs deacetylate histones NoRC negatively regulates rRNA expression mRNA Splicing - Major Pathway Potential therapeutics for SARS
Drugs
Diseases
GWAS		Basophil count ( 32888494) Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30224653)
Interacting Genes		19 interacting genes: APP BEND7 CDCA7L CDK4 CEP70 DVL2 DVL3 KIAA1191 KRTAP10-6 KRTAP10-7 MCC SAP18 SF3B3 SLC25A38 SOD2 SPANXN2 SSX2IP TERF1 TSPYL2	14 interacting genes: DEF6 ERBB3 HDAC1 IKZF1 INCA1 NOL12 NTAQ1 POLE2 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2
Entrez ID		79159	10284
HPRD ID		17537	04256
Ensembl ID		ENSG00000273899	ENSG00000150459
Uniprot IDs		Q9UGY1	O00422
PDB IDs			2HDE
Enriched GO Terms of Interacting Partners?		Frizzled Binding Positive Regulation Of Neuron Projection Arborization Response To Manganese Ion Regulation Of Neuron Projection Arborization Positive Regulation Of JNK Cascade Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of JNK Cascade Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Nitric Oxide Metabolic Process Response To Xenobiotic Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Acetylcholine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Negative Regulation Of DNA Replication Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Glycine Import Into Mitochondrion	Positive Regulation Of Stem Cell Population Maintenance Nucleoplasm Sin3-type Complex Transcription Corepressor Activity Nucleus Histone Deacetylase Complex Negative Regulation Of Stem Cell Population Maintenance Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Intermediate Filament Polymerization Ciliary Tip Ciliary Base Cellular Response To Tert-butyl Hydroperoxide Negative Regulation Of Protein Localization To Nucleus Response To Methylglyoxal Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Protein-N-terminal Glutamine Amidohydrolase Activity Negative Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Cardiac Muscle Tissue Development Regulation Of Programmed Cell Death ERBB3:ERBB2 Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Repressor Complex Krueppel-associated Box Domain Binding Intermediate Filament Polymerization Or Depolymerization Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Positive Regulation Of Response To Drug Protein-N-terminal Asparagine Amidohydrolase Activity Regulation Of Stem Cell Population Maintenance
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