FSCN1 and DNAJB9

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FSCN1	DNAJB9
Gene Name		fascin actin-bundling protein 1	DnaJ (Hsp40) homolog, subfamily B, member 9
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Actin Cytoskeleton Cell Junction Filopodium Extracellular Vesicular Exosome Invadopodium	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Drug Binding Protein Binding, Bridging Poly(A) RNA Binding Actin Filament Binding	Protein Binding Misfolded Protein Binding
	Biological Process	Cell Proliferation Cell Migration Actin Cytoskeleton Organization Cell Motility Actin Filament Bundle Assembly	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response ER-associated Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Smoking behavior ( 22006218)
Protein-Protein Interactions		10 interactors: ACTA1 ACTC1 CTNNB1 DNAJB9 MAPK8IP2 NGFR PRKCA PRKCD RAB1A YWHAQ	10 interactors: DYNLL1 FAM71C FSCN1 KIAA0368 MYL6 PLK1 RFK SLC16A8 TCEA2 TCERG1
Entrez ID		6624	4189
HPRD ID		04068	07047
Ensembl ID		ENSG00000075618	ENSG00000128590
Uniprot IDs		B3KTA3 J3KNT0 Q16658	Q6FIF1 Q9UBS3
PDB IDs		1DFC 3LLP 3O8K 3P53 4GOV 4GOY 4GP0 4GP3	2CTR
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Skeletal Muscle Thin Filament Assembly Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Cellular Response To Insulin Stimulus Skeletal Myofibril Assembly Regulation Of Protein Metabolic Process Negative Regulation Of Glial Cell Apoptotic Process Apoptotic Signaling Pathway Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Regulation Of Cell Death Response To Organic Substance Developmental Process Regulation Of Platelet Aggregation Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Glycoprotein Metabolic Process Negative Regulation Of Cell Death Response To Stimulus Cell Development Response To External Stimulus Cellular Component Assembly Positive Regulation Of Cellular Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Platelet Activation Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Hair Follicle Morphogenesis Response To Growth Factor Cellular Response To Stimulus Actin-myosin Filament Sliding Muscle Filament Sliding Neurotrophin TRK Receptor Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Cell Death Neurotrophin Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Anatomical Structure Development Cell Differentiation Defense Response Negative Regulation Of Insulin Receptor Signaling Pathway	Riboflavin Biosynthetic Process FMN Biosynthetic Process Activation Of APC-Cdc20 Complex Activity G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of NAD(P)H Oxidase Activity
Tagcloud ?		133b accurately adjacent backgroundincreasing bundling conclusionour contrary detailed evidences exerted fascin functioned gc ges introduced invasion knockdown methodswe micrornas mimics mir modulating neoplastic oncogenes pairs resultsmir suppressors taqman venous	applicable attractor bcam biomarker bionetworks calculating called cd68 consideration cxcl12 dream existing facility fgd3 hormonal lym mes metagene metagenes outperform predictions remarkable sage selector suggestion susd3 unexpected universally winning
Tagcloud (Difference) ?		133b accurately adjacent backgroundincreasing bundling conclusionour contrary detailed evidences exerted fascin functioned gc ges introduced invasion knockdown methodswe micrornas mimics mir modulating neoplastic oncogenes pairs resultsmir suppressors taqman venous	applicable attractor bcam biomarker bionetworks calculating called cd68 consideration cxcl12 dream existing facility fgd3 hormonal lym mes metagene metagenes outperform predictions remarkable sage selector suggestion susd3 unexpected universally winning
Tagcloud (Intersection) ?