SNCG and GRK1

Number of citations of the paper that reports this interaction (PubMedID 10852916)
0

Data Source:
BioGRID (enzymatic study)

		SNCG	GRK1
Description		synuclein gamma	G protein-coupled receptor kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Cytoskeleton Axon Neuronal Cell Body Axon Terminus Perinuclear Region Of Cytoplasm Extracellular Exosome	Photoreceptor Outer Segment Cytoplasm Membrane Cell Projection Photoreceptor Disc Membrane
	Molecular Function	Protein Binding Cuprous Ion Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity G Protein-coupled Receptor Kinase Activity ATP Binding Kinase Activity Transferase Activity Rhodopsin Kinase Activity
	Biological Process	Chemical Synaptic Transmission Adult Locomotory Behavior Protein Secretion Regulation Of Dopamine Secretion Regulation Of Neurotransmitter Secretion Synaptic Vesicle Endocytosis Synapse Organization	Signal Transduction Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Light Stimulus Regulation Of Signal Transduction G Protein-coupled Opsin Signaling Pathway Regulation Of Opsin-mediated Signaling Pathway Protein Autophosphorylation
Pathways			Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases			Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS
Interacting Genes		12 interacting genes: ADRB2 BUB1B GRK1 GRK5 GRK6 MAPK1 MAPK3 MAPK8 PCBP1 POT1 TERF1 TERF2IP	9 interacting genes: ADRB2 CALM1 CAV1 PDE6D RCVRN RHO SNCA SNCB SNCG
Entrez ID		6623	6011
HPRD ID		04297	01585
Ensembl ID		ENSG00000173267	ENSG00000185974
Uniprot IDs		F8W754 O76070 Q6FHG5	Q15835
PDB IDs			5AFP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Telomere Maintenance Protein Serine/threonine Kinase Activity Regulation Of Chromosome Organization Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Shelterin Complex G Protein-coupled Receptor Kinase Activity Protein Kinase Activity Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Kinase Activity Telomere Capping MAP Kinase Activity Negative Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Stress-activated MAPK Cascade Positive Regulation Of Organelle Organization Stress-activated Protein Kinase Signaling Cascade RNA-templated DNA Biosynthetic Process Positive Regulation Of DNA Metabolic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Interleukin-34-mediated Signaling Pathway Protein Phosphorylation Negative Regulation Of Telomere Maintenance Beta-adrenergic Receptor Kinase Activity Regulation Of Golgi Inheritance Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cellular Component Organization Phosphorylation Regulation Of Organelle Organization Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Phosphatase Binding Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Cellular Response To Amino Acid Starvation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Amino Acid Starvation Nucleobase-containing Compound Biosynthetic Process ATP Binding Regulation Of DNA Metabolic Process Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Telomeric D-loop Disassembly Bergmann Glial Cell Differentiation Telomeric Loop Disassembly DNA Biosynthetic Process Telomere Maintenance	Presynaptic Endocytosis Cuprous Ion Binding Endocytosis Vesicle-mediated Transport In Synapse Import Into Cell Regulation Of Metal Ion Transport Regulation Of Monoatomic Ion Transport Synaptic Vesicle Endocytosis Axon Terminus Regulation Of Calcium Ion Transport Vesicle-mediated Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cell Communication By Electrical Coupling Establishment Of Localization In Cell Regulation Of Transport Inclusion Body Regulation Of Membrane Potential Regulation Of Calcium Ion Transmembrane Transport Regulation Of Dopamine Secretion Regulation Of Muscle Contraction Receptor-mediated Endocytosis Modulation Of Chemical Synaptic Transmission Regulation Of Cardiac Muscle Cell Action Potential Visual Perception Dopamine Metabolic Process Sensory Perception Of Light Stimulus Cilium Calcium Ion Binding Regulation Of Catecholamine Secretion Phototransduction Cell Projection Regulation Of Muscle System Process Protein Sequestering Activity Catecholamine Metabolic Process Detection Of Stimulus Synapse Organization Sperm Midpiece Regulation Of Monoatomic Cation Transmembrane Transport G Protein-coupled Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Smooth Muscle Contraction Positive Regulation Of Mini Excitatory Postsynaptic Potential System Process Long-term Synaptic Potentiation Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Action Potential Inward Rectifier Potassium Channel Inhibitor Activity Positive Regulation Of Calcium Ion Transmembrane Transport Photoreceptor Inner Segment
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