SNAPC4 and SNAPC5

Number of citations: 0 (PubMedID 11056176)
Data Source: HPRD (in vivo, in vitro)

		SNAPC4	SNAPC5
Name		small nuclear RNA activating complex polypeptide 4	small nuclear RNA activating complex polypeptide 5
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm SnRNA-activating Protein Complex	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase III General Transcription Initiation Factor Activity RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
GWAS		Crohn's disease ( 21102463 22936669 28067908 ) Glucose homeostasis traits ( 25524916 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Inflammatory bowel disease ( 28067908 ) Joint damage in rheumatoid arthritis ( 26498133 ) Lymphocyte percentage of white cells ( 32888494 ) Metabolite levels ( 23823483 ) Neutrophil percentage of white cells ( 32888494 ) Takayasu arteritis ( 33308445 ) Ulcerative colitis ( 21297633 28067908 )	No GWAS studies recorded
Interacting Genes		8 interacting genes: BRF2 HNRNPD MAPK6 POU2F1 SNAPC1 SNAPC2 SNAPC5 TBP	43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2
Entrez ID		6621	10302
HPRD ID		04146	16183
Ensembl ID		ENSG00000165684	ENSG00000174446
Uniprot IDs		Q5SXM2	O75971
PDB IDs		7XUR 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
GO Terms Enriched among Interactors		RNA Polymerase II General Transcription Initiation Factor Activity Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity SnRNA Transcription Transcription By RNA Polymerase II DNA-templated Transcription SnRNA Metabolic Process DNA-templated Transcription Initiation SnRNA Transcription By RNA Polymerase III RNA Metabolic Process Nucleoplasm SnRNA Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Nucleic Acid Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nucleus Transcription Preinitiation Complex Assembly Hepatocyte Dedifferentiation Cellular Response To Putrescine Macromolecule Metabolic Process Circadian Regulation Of Translation Septin Cytoskeleton SnRNA-activating Protein Complex Transcription Factor TFIIIB Complex TFIIB-class Transcription Factor Binding Positive Regulation Of Telomere Capping MCRD-mediated MRNA Stability Complex RNA Polymerase Transcription Factor SL1 Complex Transcription Factor TFIIA Complex Response To Rapamycin Cell Dedifferentiation RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding Pronucleus Protein-DNA Complex Assembly Transcription Initiation At RNA Polymerase III Promoter Male Pronucleus Aryl Hydrocarbon Receptor Binding Response To Sodium Phosphate Minor Groove Of Adenine-thymine-rich DNA Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Female Germ Cell Nucleus Transcription Preinitiation Complex Regulation Of Telomere Capping	SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis