SNAPC4 and BRF2

Number of citations of the paper that reports this interaction (PubMedID 12621023)
0

Data Source:
HPRD (in vitro)

		SNAPC4	BRF2
Description		small nuclear RNA activating complex polypeptide 4	BRF2 general transcription factor IIIB subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm SnRNA-activating Protein Complex	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm Transcription Preinitiation Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase III General Transcription Initiation Factor Activity RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding Zinc Ion Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Metal Ion Binding
	Biological Process	SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase II Cellular Response To Oxidative Stress Transcription Preinitiation Complex Assembly
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Crohn's disease ( 21102463 22936669 28067908) Glucose homeostasis traits ( 25524916) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Joint damage in rheumatoid arthritis ( 26498133) Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483) Neutrophil percentage of white cells ( 32888494) Takayasu arteritis ( 33308445) Ulcerative colitis ( 21297633 28067908)	Axial length ( 24144296)
Interacting Genes		8 interacting genes: BRF2 HNRNPD MAPK6 POU2F1 SNAPC1 SNAPC2 SNAPC5 TBP	3 interacting genes: RBL2 SNAPC4 TBP
Entrez ID		6621	55290
HPRD ID		04146	06115
Ensembl ID		ENSG00000165684	ENSG00000104221
Uniprot IDs		Q5SXM2	Q9HAW0
PDB IDs		7XUR 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	4ROC 4ROD 4ROE 5N9G 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		RNA Polymerase II General Transcription Initiation Factor Activity Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity SnRNA Transcription Transcription By RNA Polymerase II DNA-templated Transcription SnRNA Metabolic Process DNA-templated Transcription Initiation SnRNA Transcription By RNA Polymerase III RNA Metabolic Process Nucleoplasm SnRNA Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Nucleic Acid Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nucleus Transcription Preinitiation Complex Assembly Hepatocyte Dedifferentiation Cellular Response To Putrescine Macromolecule Metabolic Process Circadian Regulation Of Translation Septin Cytoskeleton SnRNA-activating Protein Complex Transcription Factor TFIIIB Complex TFIIB-class Transcription Factor Binding Positive Regulation Of Telomere Capping MCRD-mediated MRNA Stability Complex RNA Polymerase Transcription Factor SL1 Complex Transcription Factor TFIIA Complex Response To Rapamycin Cell Dedifferentiation RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding Pronucleus Protein-DNA Complex Assembly Transcription Initiation At RNA Polymerase III Promoter Male Pronucleus Aryl Hydrocarbon Receptor Binding Response To Sodium Phosphate Minor Groove Of Adenine-thymine-rich DNA Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Female Germ Cell Nucleus Transcription Preinitiation Complex Regulation Of Telomere Capping	RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III RNA Polymerase II General Transcription Initiation Factor Activity DNA Binding Regulation Of Lipid Kinase Activity SnRNA Transcription By RNA Polymerase II DNA-templated Transcription SnRNA-activating Protein Complex SnRNA Transcription By RNA Polymerase III RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Transcription By RNA Polymerase II RNA Polymerase Transcription Factor SL1 Complex TFIIB-class Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Binding Male Pronucleus Transcription Factor TFIIA Complex Aryl Hydrocarbon Receptor Binding Pronucleus RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus Female Germ Cell Nucleus SnRNA Transcription Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor TFIID Complex Nucleobase-containing Compound Biosynthetic Process MRNA Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter SnRNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Preinitiation Complex Assembly Male Germ Cell Nucleus Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Chromatin MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Euchromatin Nucleoplasm Promoter-specific Chromatin Binding Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation
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