SNAPC2 and SNAPC4

Number of citations of the paper that reports this interaction (PMID 8524284)
38

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, in vivo)

		SNAPC2	SNAPC4
Gene Name		small nuclear RNA activating complex, polypeptide 2, 45kDa	small nuclear RNA activating complex, polypeptide 4, 190kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm SnRNA-activating Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter SnRNA Transcription Gene Expression	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter SnRNA Transcription Gene Expression SnRNA Transcription From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase III Promoter
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation	RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS			Crohn's disease ( 22936669 21102463) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		2 interactors: SNAPC4 TBP	8 interactors: BRF2 HNRNPD MAPK6 POU2F1 SNAPC1 SNAPC2 SNAPC5 TBP
Entrez ID		6618	6621
HPRD ID		05464	04146
Ensembl ID		ENSG00000104976	ENSG00000165684
Uniprot IDs		Q13487	Q5SXM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase III Promoter SnRNA Transcription From RNA Polymerase III Promoter SnRNA Transcription From RNA Polymerase II Promoter SnRNA Transcription Chromatin Silencing At RDNA Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Chromatin Silencing SnRNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation Gene Silencing Transcription, DNA-templated RNA Biosynthetic Process	Transcription From RNA Polymerase III Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Nitrogen Compound Metabolic Process Cellular Metabolic Process RNA Catabolic Process Regulation Of Metabolic Process Circadian Regulation Of Translation Olfactory Placode Formation SnRNA Transcription Lens Induction In Camera-type Eye Regulation Of Cellular Process Transcription Initiation From RNA Polymerase III Promoter Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Chromatin Silencing At RDNA Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MRNA Catabolic Process Nose Development Positive Regulation Of Transcription, DNA-templated Definitive Hemopoiesis Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Somatic Stem Cell Division Transcription Initiation From RNA Polymerase I Promoter Lens Morphogenesis In Camera-type Eye Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase I Promoter Negative Regulation Of Stem Cell Differentiation Positive Regulation Of Gene Expression
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