PACRGL and ALX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PACRGL	ALX1
Description		parkin coregulated like	ALX homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus Nuclear Body
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Neural Tube Closure Regulation Of DNA-templated Transcription Anterior/posterior Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Mesenchymal Cell Development Embryonic Limb Morphogenesis Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Neuron Development Embryonic Skeletal System Morphogenesis Stem Cell Development Roof Of Mouth Development
Pathways
Drugs
Diseases			Frontonasal dysplasia
GWAS		Serum metabolite concentrations in chronic kidney disease ( 29545352)	Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)
Interacting Genes		14 interacting genes: ALX1 BEX5 FAM3A GOLGA2 GRB2 MYF5 MYOG PIK3R3 RCN3 TASOR2 TRIM55 TRIM63 TXNRD3 ZBTB10	17 interacting genes: ALX4 APCS CLIC3 CREBBP EEF1D EP300 GRP IPO13 KAT5 KRTAP4-4 OR52L1 PACRGL RARA RBM45 SRA1 UROC1 ZNF300
Entrez ID		133015	8092
HPRD ID		14537	03316
Ensembl ID		ENSG00000163138	ENSG00000180318
Uniprot IDs		A8K679 D6RGK2 Q8N7B6	Q15699 V9HWA7
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Fiber Development Muscle Atrophy Striated Muscle Atrophy Regulation Of Skeletal Muscle Fiber Development Muscle Cell Fate Commitment Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Tissue Development Response To Electrical Stimulus Phosphotyrosine Residue Binding Regulation Of Striated Muscle Tissue Development Regulation Of Myotube Differentiation Regulation Of Muscle Organ Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Guanyl-nucleotide Exchange Factor Adaptor Activity E-box Binding Skeletal Muscle Cell Differentiation Skeletal Muscle Tissue Development Grb2-EGFR Complex Regulation Of Myoblast Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Atrophy Negative Regulation Of Antifungal Innate Immune Response Immune Response Insulin Receptor Signaling Pathway Embryonic Skeletal System Morphogenesis Microtubule Regulation Of Striated Muscle Cell Differentiation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Defense Response To Symbiont Defense Response To Other Organism Negative Regulation Of Innate Immune Response RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Peptide Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Acetylation Acetyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Transcription Regulator Complex Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone Acetyltransferase Activity Protein Acetylation Transcription Coactivator Binding DNA-binding Transcription Factor Binding N-terminal Protein Amino Acid Acetylation Histone H4 Acetyltransferase Activity Chromatin DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity Positive Regulation Of RNA Metabolic Process Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of T Cell Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of T-helper Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Negative Regulation Of Myoblast Differentiation Acyltransferase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Radiation Regulation Of Defense Response Regulation Of Hemopoiesis Innate Immune Response-activating Signaling Pathway Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Response To Radiation Tau Protein Binding Positive Regulation Of Defense Response Positive Regulation Of Leukocyte Differentiation Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?