SLC19A1 and SH3BGR

Data Source: HiPPIP (Novel)

		SLC19A1	SH3BGR
Name		solute carrier family 19 member 1	SH3 domain binding glutamate rich protein
Structure			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding Folic Acid Binding Organic Anion Transmembrane Transporter Activity Folic Acid Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Antiporter Activity Methotrexate Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity 2',3'-cyclic GMP-AMP Binding Vitamin Transmembrane Transporter Activity Cyclic-GMP-AMP Transmembrane Transporter Activity	Protein Binding SH3 Domain Binding
	Biological Process	Xenobiotic Transmembrane Transport Female Pregnancy Response To Xenobiotic Stimulus Response To Toxic Substance Organic Anion Transport Folic Acid Transport Folic Acid Metabolic Process Vitamin Transport Methotrexate Transport Monoatomic Anion Transmembrane Transport Folate Transmembrane Transport Cyclic-GMP-AMP Transmembrane Import Across Plasma Membrane Positive Regulation Of CGAS/STING Signaling Pathway Transport Across Blood-brain Barrier Folate Import Across Plasma Membrane	None
Pathways		Metabolism of folate and pterines	None
GWAS		Ankle injury ( 28957384 )	No GWAS studies recorded
Novel Interactors		2 novel interactors: SH3BGR TRAPPC10	5 novel interactors: PCNT PWP2 SLC19A1 SMAD7 TFF3
Interacting Genes		1 interacting genes: KRT26	2 interacting genes: CAPN1 FCHSD2
Entrez ID		6573	6450
HPRD ID		02691	03753
Ensembl ID		ENSG00000173638	ENSG00000185437
Uniprot IDs		P41440	A0A804CBI3 C9JJT2 P55822
PDB IDs		7TX6 7TX7 7XPZ 7XQ0 7XQ1 7XQ2 7XTK 8DEP 8GOE 8GOF 8HII 8HIJ 8HIK 9JOZ 9JRI 9JRK 9JRL 9JRM 9JRN	Not available
GO Terms Enriched among Interactors		TRAPPII Protein Complex TRAPP Complex Early Endosome To Golgi Transport	Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Stereocilium Shaft Positive Regulation Of Chondrocyte Development Folate Import Across Plasma Membrane 2',3'-cyclic GMP-AMP Binding Cyclic-GMP-AMP Transmembrane Transporter Activity