SLC10A1 and ACSL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC10A1	ACSL5
Description		solute carrier family 10 member 1	acyl-CoA synthetase long chain family member 5
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity Bile Acid Transmembrane Transporter Activity Symporter Activity	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Ligase Activity Arachidonate-CoA Ligase Activity Oleoyl-CoA Ligase Activity
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Lipid Transport Bile Acid And Bile Salt Transport Response To Nutrient Levels Response To Estrogen Response To Ethanol Symbiont Entry Into Host Cell Transmembrane Transport Cellular Response To Xenobiotic Stimulus	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Positive Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Long-chain Fatty-acyl-CoA Biosynthetic Process Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Recycling of bile acids and salts	Synthesis of very long-chain fatty acyl-CoAs
Drugs		Bulevirtide
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)	Amyotrophic lateral sclerosis ( 32968195) Basophil percentage of white cells ( 32888494) High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Mean platelet volume ( 27863252 32888494) Platelet count ( 32888494)
Interacting Genes		115 interacting genes: ABHD16A ACSL5 AGPAT3 APOL3 ARL6IP6 ASGR1 ATP13A1 ATP6V0B BMP10 BTN2A2 C2 C3orf52 C8A CDIPT CFHR5 CFTR CLDN19 CMTM3 COX20 CXCL9 CYB5B CYB5R3 DERL1 DGAT2L6 EMC6 EMD FA2H FAM241B FAXDC2 FCER1G FDFT1 FKBP8 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP INSIG2 LNPEP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 NKG7 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 PMP22 RABAC1 RTP2 RUSF1 SACM1L SCAMP4 SEC22A SELENOK SERP1 SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STATH STX12 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMEM97 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UBIAD1 UNC50 UPK1B VAMP3 VAPB YIF1A YIPF4 YIPF6	13 interacting genes: AQP6 CREB3 EBAG9 FBXO7 PEX12 RETREG3 SELENOI SLC10A1 SLC10A6 SLC16A7 SLC35H1 SLC7A14 TMEM14B
Entrez ID		6554	51703
HPRD ID		01672	16139
Ensembl ID		ENSG00000100652	ENSG00000197142
Uniprot IDs		B2RA41 Q14973	A0A8C8L3F5 Q9ULC5
PDB IDs		7FCI 7PQG 7PQQ 7VAD 7VAG 7WSI 7ZYI 8HRX 8HRY 8RQF
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Protein Binding Endomembrane System Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Negative Regulation Of Sphingolipid Biosynthetic Process Membrane Organization Serine Palmitoyltransferase Complex Establishment Of Protein Localization To Membrane Establishment Of Protein Localization Cellular Localization Plasma Membrane Steroid Biosynthetic Process Vesicle-mediated Transport Lipid Metabolic Process Membrane Docking Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Ceramide Metabolic Process Myelination Axon Ensheathment Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Golgi Membrane Protein Insertion Into Membrane Protein Transport Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Nitric-oxide Synthase Complex Transmembrane Transport Organelle Localization By Membrane Tethering Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Lysosomal Membrane Sterol Metabolic Process SNARE Complex Organelle Fusion Sphingomyelin Metabolic Process Amino Acid Transmembrane Transport Regulation Of Membrane Lipid Metabolic Process Nuclear Inner Membrane Phospholipid Metabolic Process Nitrite Reductase (NO-forming) Activity	Transmembrane Transport Bile Acid:sodium Symporter Activity Organic Anion Transport Carboxylic Acid Transport Organic Acid Transport Symporter Activity Membrane Bile Acid And Bile Salt Transport Monocarboxylic Acid Transport Organic Hydroxy Compound Transport Nitrate Transmembrane Transporter Activity Pyruvate Secondary Active Transmembrane Transporter Activity Positive Regulation Of Deacetylase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Autophagy Secondary Active Monocarboxylate Transmembrane Transporter Activity Peroxisomal Importomer Complex Adaptive Immune Memory Response Involving T Cells And B Cells Lewy Body Core UDP-glucose Transmembrane Transport Ethanolaminephosphotransferase Activity Adaptive Immune Memory Response Pyruvate Transmembrane Transporter Activity Endoplasmic Reticulum-autophagosome Adaptor Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Peptidase Activator Activity Involved In Apoptotic Process Plasma Membrane Lactate Transport Pyruvate Transmembrane Transport Release From Viral Latency Protein O-linked Glycosylation Via Fucose Protein Import Into Peroxisome Matrix, Substrate Release Lactate Transmembrane Transporter Activity Pyruvate Transport CCR1 Chemokine Receptor Binding Gamma-aminobutyric Acid Import Gamma-aminobutyric Acid Transmembrane Transporter Activity
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