LGALS7B and HSPA6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LGALS7B	HSPA6
Description		galectin 7B	heat shock protein family A (Hsp70) member 6
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Extracellular Exosome	Extracellular Region Nucleus Cytoplasm Centriole Cytosol Plasma Membrane COP9 Signalosome Secretory Granule Lumen Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Carbohydrate Binding	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity Enzyme Binding Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding ATP-dependent Protein Folding Chaperone
	Biological Process	Apoptotic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules	Protein Folding Response To Unfolded Protein Cellular Response To Heat Protein Refolding Cellular Heat Acclimation
Pathways		Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Regulation of HSF1-mediated heat shock response Neutrophil degranulation
Drugs		Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Alanine aminotransferase levels ( 33547301) Birth weight ( 31043758) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Helicobacter pylori serologic status ( 23652523) Inflammatory bowel disease ( 23128233 28067908) Offspring birth weight ( 31043758) Ulcerative colitis ( 21297633 28067908)
Interacting Genes		6 interacting genes: HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2	18 interacting genes: ADCK5 AHCYL1 BAG4 C22orf15 CISH COMMD6 CYP4F12 DNAJB4 FLNA KRT222 LGALS7 LGALS7B PPIB PRAP1 RPA1 SNCA TERF1 WEE2-AS1
Entrez ID		653499	3310
HPRD ID		19145	00775
Ensembl ID		ENSG00000178934	ENSG00000173110
Uniprot IDs		P47929	A0A384NKX5 B3KSM6 P17066
PDB IDs		1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S 6VTO 6VTP 6VTQ 6VTR 6VTS 7N4O 7N57 7N6C 7N8D 7N8G 7N96 7RDG 7TKW 7TKX 7TKY 7TKZ 7TRN 7TRO 7XAC 7XBL	3FE1
Enriched GO Terms of Interacting Partners?			Regulation Of B Cell Antigen Processing And Presentation Negative Regulation Of Exocytosis Immune Complex Clearance By Monocytes And Macrophages Negative Regulation Of Type I Hypersensitivity Negative Regulation Of Antibody-dependent Cellular Cytotoxicity Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Regulation Of Protein Stability Positive Regulation Of Organelle Organization Protein Sequestering Activity Intracellular Membrane-bounded Organelle Telomere Maintenance Via Telomere Lengthening RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomerase G-rich Strand Telomeric DNA Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of MRNA Modification Positive Regulation Of Triglyceride Transport Positive Regulation Of Monoatomic Ion Transport Positive Regulation Of Cellular Component Organization
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