AQP12B and TMEM97

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AQP12B	TMEM97
Description		aquaporin 12B	transmembrane protein 97
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Nucleus Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	Protein Binding Water Channel Activity Channel Activity	Protein Binding Oxysterol Binding Cholesterol Binding
	Biological Process	Water Transport Transmembrane Transport	Regulation Of Cell Growth Regulation Of Intracellular Lipid Transport Regulation Of Intracellular Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Wound Healing Positive Regulation Of Lipoprotein Transport
Pathways
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Osteoprotegerin levels ( 25080503)
Interacting Genes		4 interacting genes: AGPAT4 STRIT1 TMEM97 TRARG1	66 interacting genes: APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CD79A CGRRF1 CLDN7 CLSTN3 CPLX4 EBP ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJA8 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 PDCD1LG2 PDZK1IP1 PLP1 PSCA REEP1 RHCG RNF170 SAR1A SGPL1 SLC10A1 SLC14A1 SLC14A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 VSIR
Entrez ID		653437	27346
HPRD ID		19650	14343
Ensembl ID		ENSG00000185176	ENSG00000109084
Uniprot IDs		A6NM10 Q8IUS6	Q5BJF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Transport Positive Regulation Of Lipoprotein Transport Endomembrane System Glucose Import In Response To Insulin Stimulus Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction Rough Endoplasmic Reticulum Membrane Regulation Of Intracellular Cholesterol Transport Regulation Of Intracellular Lipid Transport Lysophosphatidic Acid Acyltransferase Activity CDP-diacylglycerol Biosynthetic Process Vesicle Fusion To Plasma Membrane CDP-diacylglycerol Metabolic Process Endosome To Plasma Membrane Protein Transport Oxysterol Binding 1-acylglycerol-3-phosphate O-acyltransferase Activity D-glucose Import Regulation Of Skeletal Muscle Contraction Regulation Of Cellular Localization Positive Regulation Of Calcium Ion Import Phosphatidic Acid Biosynthetic Process D-glucose Transmembrane Transport Rough Endoplasmic Reticulum Phosphatidic Acid Metabolic Process Hexose Transmembrane Transport Regulation Of ATP-dependent Activity Regulation Of Cardiac Muscle Cell Contraction Sarcoplasmic Reticulum Membrane Carbohydrate Transmembrane Transport Regulation Of Calcium Ion Import	Membrane Water Transport One-carbon Compound Transport Fluid Transport Protein Binding Water Channel Activity Endoplasmic Reticulum Membrane Connexin Complex Endoplasmic Reticulum Gap Junction Channel Activity Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Mitochondrial Membrane Gap Junction Urea Transmembrane Transporter Activity Transmembrane Transport
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