ARV1 and RNASEK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARV1	RNASEK
Description		ARV1 fatty acid homeostasis modulator	ribonuclease K
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cortical Endoplasmic Reticulum	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex
	Molecular Function	Protein Binding Sterol Transfer Activity	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Cholesterol Biosynthetic Process Lipid Transport Steroid Metabolic Process Cholesterol Metabolic Process Bile Acid Metabolic Process Sterol Metabolic Process Cholesterol Transport Intracellular Sterol Transport Regulation Of Intracellular Cholesterol Transport Regulation Of Cholesterol Metabolic Process Regulation Of Plasma Membrane Sterol Distribution	Monoatomic Ion Transport Endocytosis Receptor-mediated Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Receptor-mediated Endocytosis Of Virus By Host Cell Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport
Pathways		Cholesterol biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		15 interacting genes: ADRB2 AQP6 CREB3L1 EBP FAM209A GPR152 MUC1 RNASEK SCN3B SLC10A6 SMO TLCD4 TMEM14B TMEM31 TMX2	26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21
Entrez ID		64801	440400
HPRD ID		12494	17568
Ensembl ID		ENSG00000173409	ENSG00000219200
Uniprot IDs		Q9H2C2	A0A0C4DH89 Q6P5S7
PDB IDs			6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Membrane Organization Chloride Channel Inhibitor Activity Establishment Of Protein Localization Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Calcium Ion Homeostasis Cellular Localization Organelle Localization By Membrane Tethering Protein Targeting Calcium Ion Homeostasis Membrane Docking Positive Regulation Of Mitochondrial Fission Intracellular Chemical Homeostasis Regulation Of Mitochondrial Fission Mitochondrion Autophagosome Adaptor Activity Amyloid Fibril Formation Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Protein Targeting To Mitochondrion Cysteinyl Leukotriene Receptor Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Regulation Of Plasma Membrane Sterol Distribution G Protein-coupled Amine Receptor Activity Membrane Fusion Macroautophagy
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