CERK and KRTAP3-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CERK	KRTAP3-1
Description		ceramide kinase	keratin associated protein 3-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Ceramide Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Lipid Metabolic Process Ceramide Metabolic Process Glycosphingolipid Biosynthetic Process
Pathways		Glycosphingolipid biosynthesis	Keratinization
Drugs
Diseases
GWAS		Aseptic loosening in total joint arthroplasty ( 31791832) Triglyceride levels ( 30108155)
Interacting Genes		21 interacting genes: ALAS1 APP CRYBA1 CYSRT1 KRT34 KRTAP1-1 KRTAP10-3 KRTAP11-1 KRTAP19-1 KRTAP19-6 KRTAP3-1 KRTAP3-2 KRTAP6-2 KRTAP9-2 MTUS2 NBPF19 NHLRC4 NOTCH2NLA OIP5 PLEKHF2 TRIM42	83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		64781	83896
HPRD ID		09878	13937
Ensembl ID		ENSG00000100422	ENSG00000212901
Uniprot IDs		Q8TCT0	Q9BYR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Molecule Activity	Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion
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