FNDC3B and NCAM2

Number of citations of the paper that reports this interaction (PubMedID 36811957)
49

Data Source:
BioGRID (unspecified method)

		FNDC3B	NCAM2
Description		fibronectin type III domain containing 3B	neural cell adhesion molecule 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endomembrane System Membrane	Plasma Membrane Membrane Nuclear Body Axon Neuron Projection Synaptic Membrane
	Molecular Function	RNA Binding Protein Binding	Identical Protein Binding
	Biological Process		Cell Adhesion Neuron Cell-cell Adhesion Axonal Fasciculation
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bell's palsy ( 33602968) Central corneal thickness ( 29760442 30894546 31798171 32528159) Corneal hysteresis ( 30894546) Corneal resistance factor ( 30894546 31246245) Corneal structure ( 23291589) Coronary artery disease ( 33020668 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma (primary open-angle) ( 33627673) Glycated hemoglobin levels ( 34059833 28898252) Heart rate ( 23583979) Height ( 31562340 33713608 23563607 28552196 25282103 25429064) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hypertrophic cardiomyopathy ( 33495597 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 25173106 31798171 28073927 29785010 30054594 29617998 29235454) Intraocular pressure (Goldman correlated) ( 30894546) Keratoconus ( 33649486) Mean corpuscular hemoglobin ( 32888494) Myocardial infarction ( 33532862) Parkinson's disease ( 26227905) PR interval ( 32439900) Pulse pressure ( 30224653) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triptolide cytotoxicity ( 26121980) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 34021172 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Asthma ( 29273806) Blood protein levels ( 30072576) Colorectal or endometrial cancer ( 26621817) Diisocyanate-induced asthma ( 25918132) Endometrial cancer (endometrioid histology) ( 30093612) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) HOMA-B (corrected for HOMA-IR) ( 30369944) Longevity ( 20834067) Metabolite levels ( 23823483) Obesity ( 21552555) Rosacea symptom severity ( 29771307) Venous thromboembolism ( 33592630) Visceral fat ( 22589738)
Interacting Genes		124 interacting genes: ABHD11 ABHD8 ACTG1 ACTMAP ADGRF5 AHNAK ALB ANXA2 ATP1A1 ATP5F1A BBS2 BICRAL BRWD1 C10orf55 C22orf15 CAMK2D CAP1 CAPN3 CDC42 CEMP1 CFL1 DAPL1 DSTN DUSP10 EEF1E1 EGFR EIF5A2 ENO1 ERCC6 ERH ERI3 FUS GAS2L3 GOLT1B GTF2F1 HAPLN2 HNRNPD HNRNPK HSP90AB4P HSPA1A HSPA5 HSPA7 HSPA8 HSPB1 HSPD1 HSPH1 KARS1 KLHDC7B KRTAP11-1 L3MBTL3 LARP4 MBD3L1 MBOAT7 MCCD1 MVP MYH14 MYL6 NAGK NCAM2 NCK1 NDUFAB1 P4HB PARP1 PC PGK1 PIK3R4 PKLR POGZ POU6F2 PPP6R2 PRKAA2 PSMA3 PTMA RAB1A RAB1B RAN REL RPL12 RPL15 RPL17 RPL23 RPL28 RPL34 RPS14 RPS3 RPS3A RPS6 RUSC1 SNRPD3 SOD1 SPCS2 SPMIP10 SPMIP5 SPSB2 SRARP STPG4 SUGT1 SUOX SYNCRIP TEKT5 TEPSIN TESMIN TEX48 TGM2 TIAM1 TKT TOX4 TPM3 TRAF2 TRIM16 TRIM35 TRIM42 TRIP13 TTN TUBB4A TUBGCP6 TXN UBA52 UBAP2 USP54 VAC14 YPEL3 YWHAZ ZMYND19	11 interacting genes: CHD4 CTNND2 FNDC3B PRNP RSPH1 SCG3 YWHAB YWHAE YWHAG YWHAH YWHAZ
Entrez ID		64778	4685
HPRD ID		10943	03619
Ensembl ID		ENSG00000075420	ENSG00000154654
Uniprot IDs		Q53EP0	O15394
PDB IDs			2DOC 2JLL 2KBG 2V5T 2VAJ 2WIM 2XY1 2XY2 2XYC
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Cytosol Cytoplasm Cytoplasmic Translation Cytosolic Ribosome Focal Adhesion Ribonucleoprotein Complex RNA Binding ATP-dependent Protein Folding Chaperone Translation Structural Constituent Of Ribosome Ribosome Protein Refolding Cadherin Binding Cytosolic Large Ribosomal Subunit Protein-containing Complex Melanosome Protein Binding Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding ATP Metabolic Process Protein Metabolic Process Protein Phosphatase Binding Cytosolic Small Ribosomal Subunit Regulation Of Intrinsic Apoptotic Signaling Pathway Protein-folding Chaperone Binding Nucleotide Binding Response To Nitric Oxide Protein Folding Positive Regulation Of Protein Metabolic Process Organophosphate Metabolic Process Enzyme Binding Actin Filament-based Process Macromolecule Metabolic Process Nucleotide Metabolic Process Nucleus Vesicle Structural Molecule Activity Conferring Elasticity Purine Nucleotide Metabolic Process Protein Folding Chaperone Nucleobase-containing Small Molecule Metabolic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway ATP Binding Positive Regulation Of Gene Expression Nicotinamide Nucleotide Metabolic Process Unfolded Protein Binding Nucleoside Phosphate Metabolic Process Cellular Response To Nitric Oxide	Phosphoserine Residue Binding Protein Sequestering Activity Protein Domain Specific Binding Cerebellar Granule Cell To Purkinje Cell Synapse Transmembrane Transporter Binding Protein Targeting Cadherin Binding Melanosome Insulin-like Growth Factor Receptor Binding Histone Deacetylase Binding Focal Adhesion Regulation Of Protein Localization Dendritic Spine Organization Neuron Projection Organization Postsynapse Organization Regulation Of Synaptic Plasticity Negative Regulation Of Immune System Process Identical Protein Binding Intracellular Protein Localization Phosphoprotein Binding Protein Phosphatase Inhibitor Activity Substantia Nigra Development Negative Regulation Of Protein Localization To Nucleus Cellular Response To Glucose Starvation Regulation Of Synapse Organization Regulation Of Potassium Ion Transmembrane Transport Extracellular Exosome Type 8 Metabotropic Glutamate Receptor Binding Establishment Of Protein Localization Neural Nucleus Development Negative Regulation Of TORC1 Signaling TORC1 Signaling Glucocorticoid Catabolic Process Cytoplasm Negative Regulation Of Signal Transduction Regulation Of Potassium Ion Transport Regulation Of Metal Ion Transport Regulation Of Heart Rate By Hormone TOR Signaling Synaptic Target Recognition Regulation Of Protein Stability Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of TOR Signaling RNA Binding Protein Phosphatase Binding Enzyme Binding Regulation Of TORC1 Signaling Protein Kinase C Inhibitor Activity Protein Localization To Secretory Granule
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?