NCAM2 and SCG3

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		NCAM2	SCG3
Description		neural cell adhesion molecule 2	secretogranin III
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Nuclear Body Axon Neuron Projection Synaptic Membrane	Extracellular Region Endoplasmic Reticulum Lumen Membrane Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Secretory Granule Lumen
	Molecular Function	Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Axonal Fasciculation	Protein Localization To Secretory Granule
Pathways			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Asthma ( 29273806) Blood protein levels ( 30072576) Colorectal or endometrial cancer ( 26621817) Diisocyanate-induced asthma ( 25918132) Endometrial cancer (endometrioid histology) ( 30093612) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) HOMA-B (corrected for HOMA-IR) ( 30369944) Longevity ( 20834067) Metabolite levels ( 23823483) Obesity ( 21552555) Rosacea symptom severity ( 29771307) Venous thromboembolism ( 33592630) Visceral fat ( 22589738)	Asthma ( 20159242) Blood protein levels ( 30072576) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494)
Interacting Genes		11 interacting genes: CHD4 CTNND2 FNDC3B PRNP RSPH1 SCG3 YWHAB YWHAE YWHAG YWHAH YWHAZ	5 interacting genes: CHGA DNM1L NCAM2 NRIP1 SDCBP
Entrez ID		4685	29106
HPRD ID		03619	11538
Ensembl ID		ENSG00000154654	ENSG00000104112
Uniprot IDs		O15394	Q8WXD2
PDB IDs		2DOC 2JLL 2KBG 2V5T 2VAJ 2WIM 2XY1 2XY2 2XYC
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Sequestering Activity Protein Domain Specific Binding Cerebellar Granule Cell To Purkinje Cell Synapse Transmembrane Transporter Binding Protein Targeting Cadherin Binding Melanosome Insulin-like Growth Factor Receptor Binding Histone Deacetylase Binding Focal Adhesion Regulation Of Protein Localization Dendritic Spine Organization Neuron Projection Organization Postsynapse Organization Regulation Of Synaptic Plasticity Negative Regulation Of Immune System Process Identical Protein Binding Intracellular Protein Localization Phosphoprotein Binding Protein Phosphatase Inhibitor Activity Substantia Nigra Development Negative Regulation Of Protein Localization To Nucleus Cellular Response To Glucose Starvation Regulation Of Synapse Organization Regulation Of Potassium Ion Transmembrane Transport Extracellular Exosome Type 8 Metabotropic Glutamate Receptor Binding Establishment Of Protein Localization Neural Nucleus Development Negative Regulation Of TORC1 Signaling TORC1 Signaling Glucocorticoid Catabolic Process Cytoplasm Negative Regulation Of Signal Transduction Regulation Of Potassium Ion Transport Regulation Of Metal Ion Transport Regulation Of Heart Rate By Hormone TOR Signaling Synaptic Target Recognition Regulation Of Protein Stability Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of TOR Signaling RNA Binding Protein Phosphatase Binding Enzyme Binding Regulation Of TORC1 Signaling Protein Kinase C Inhibitor Activity Protein Localization To Secretory Granule	Positive Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Dense Core Granule Biogenesis Mast Cell Chemotaxis Regulation Of Secretion Chromaffin Granule Regulation Of Secretion By Cell Protein Localization To Secretory Granule Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Ovarian Follicle Rupture Mitochondrion-derived Vesicle Mitochondrial Membrane Fission Regulation Of Peroxisome Organization Mitocytosis Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Mast Cell Migration Regulation Of Extracellular Exosome Assembly Response To Gonadotropin-releasing Hormone Intracellular Distribution Of Mitochondria
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