NUCKS1 and AK5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUCKS1	AK5
Gene Name		nuclear casein kinase and cyclin-dependent kinase substrate 1	adenylate kinase 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Microtubule Organizing Center Cytosol
	Molecular Function	Poly(A) RNA Binding	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding Nucleoside Kinase Activity
	Biological Process		Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process ATP Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways			Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Parkinson's disease ( 19915575 19915576) Prostate-specific antigen levels ( 23269536) Pubertal anthropometrics ( 23449627)
Protein-Protein Interactions		2 interactors: AK5 GLP1R	7 interactors: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH
Entrez ID		64710	26289
HPRD ID		11406	10472
Ensembl ID		ENSG00000069275	ENSG00000154027
Uniprot IDs		B4DTY3 Q9H1E3	Q9Y6K8
PDB IDs			2BWJ
Enriched GO Terms of Interacting Partners?		DADP Biosynthetic Process ADP Biosynthetic Process Deoxyribonucleoside Diphosphate Metabolic Process Nucleoside Diphosphate Biosynthetic Process ADP Metabolic Process Deoxyribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion CAMP-mediated Signaling Activation Of Adenylate Cyclase Activity Cyclic-nucleotide-mediated Signaling Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Positive Regulation Of Lyase Activity Deoxyribonucleotide Metabolic Process Response To Glucagon Pyrimidine Nucleotide Biosynthetic Process Regulation Of Adenylate Cyclase Activity Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleotide Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Regulation Of CAMP Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Regulation Of CAMP Metabolic Process Nucleoside Monophosphate Biosynthetic Process Small Molecule Metabolic Process ATP Metabolic Process Energy Reserve Metabolic Process Second-messenger-mediated Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Heart Contraction Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Cytosolic Calcium Ion Homeostasis Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Purine Nucleoside Metabolic Process Regulation Of Hormone Secretion Learning Or Memory Cognition Cellular Calcium Ion Homeostasis Ribonucleotide Metabolic Process Nucleoside Metabolic Process	UDP-glucuronate Biosynthetic Process UDP-glucuronate Metabolic Process
Tagcloud ?		association associations carcinoma casein clinicopathological cytokeratin distant epidermal estrogen grade grading histological histopathological immunohistochemical invasive involvement ki lymph markers metastases node pr progesterone regard special substrate subtype ubiquitous
Tagcloud (Difference) ?		association associations carcinoma casein clinicopathological cytokeratin distant epidermal estrogen grade grading histological histopathological immunohistochemical invasive involvement ki lymph markers metastases node pr progesterone regard special substrate subtype ubiquitous
Tagcloud (Intersection) ?