SYCE3 and SGF29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYCE3	SGF29
Description		synaptonemal complex central element protein 3	SAGA complex associated factor 29
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GO Annotations	Cellular Component	Central Element Nucleus Chromosome	SAGA Complex Nucleus Nucleoplasm SAGA-type Complex Mitotic Spindle ATAC Complex
	Molecular Function	Protein Binding	Protein Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity Methylation-dependent Protein Binding
	Biological Process	Apoptotic Process Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Spermatogenesis Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Developmental Process Cell Division Meiotic Cell Cycle Positive Regulation Of Reproductive Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of RNA Splicing Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Chromatin
Pathways		Meiotic synapsis	HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		7 interacting genes: BLOC1S6 HAUS1 INPP1 KRT79 PKN1 SGF29 TRIM54	26 interacting genes: C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KRT13 KRT15 KRT16 KRT19 KRT24 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TRAF3IP1
Entrez ID		644186	112869
HPRD ID			13996
Ensembl ID		ENSG00000217442	ENSG00000176476
Uniprot IDs		A1L190	Q96ES7
PDB IDs		6H86	3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M
Enriched GO Terms of Interacting Partners?		Inositol-1,3,4-trisphosphate 1-phosphatase Activity Inositol-1,4-bisphosphate 1-phosphatase Activity Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Tissue Morphogenesis Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Central Element Supramolecular Fiber Organization Hair Cycle Protein-DNA Complex Assembly Synaptonemal Complex Assembly Structural Constituent Of Cytoskeleton Synaptonemal Complex Organization Core Mediator Complex Organelle Organization Anatomical Structure Morphogenesis Protein Binding Spine Apparatus Assembly Mediator Complex
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