SGF29 and KRT13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SGF29	KRT13
Description		SAGA complex associated factor 29	keratin 13
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm SAGA-type Complex Mitotic Spindle ATAC Complex	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity Methylation-dependent Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of RNA Splicing Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Chromatin	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Regulation Of Translation In Response To Stress Intermediate Filament Organization
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	Keratinization Formation of the cornified envelope
Drugs
Diseases			White sponge nevus
GWAS
Interacting Genes		26 interacting genes: C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KRT13 KRT15 KRT16 KRT19 KRT24 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TRAF3IP1	70 interacting genes: ABI2 ABI3 AIRIM AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf216 CATSPERT CCHCR1 CCNC CEP57 CEP57L1 CFTR DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 LSM2 MOS MYH1 MYO15B NEFL NEIL3 PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688
Entrez ID		112869	3860
HPRD ID		13996	01016
Ensembl ID		ENSG00000176476	ENSG00000171401
Uniprot IDs		Q96ES7	A1A4E9 P13646
PDB IDs		3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Tissue Morphogenesis Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Central Element Supramolecular Fiber Organization Hair Cycle Protein-DNA Complex Assembly Synaptonemal Complex Assembly Structural Constituent Of Cytoskeleton Synaptonemal Complex Organization Core Mediator Complex Organelle Organization Anatomical Structure Morphogenesis Protein Binding Spine Apparatus Assembly Mediator Complex	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Intermediate Filament Polymerization Or Depolymerization Extracellular Exosome Cytoskeleton Cytoplasm Protein Binding Proteasome Core Complex Epidermis Development Actin-based Cell Projection
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