SGF29 and TEX12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SGF29	TEX12
Description		SAGA complex associated factor 29	testis expressed 12
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm SAGA-type Complex Mitotic Spindle ATAC Complex	Synaptonemal Complex Central Element Chromosome
	Molecular Function	Protein Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity Methylation-dependent Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of RNA Splicing Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Chromatin	Meiotic DNA Repair Synthesis Synaptonemal Complex Assembly Meiotic Cell Cycle
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	Meiotic synapsis
Drugs
Diseases
GWAS			Inflammatory biomarkers ( 24182552)
Interacting Genes		26 interacting genes: C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KRT13 KRT15 KRT16 KRT19 KRT24 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TRAF3IP1	19 interacting genes: AIMP2 AP2B1 CCNC CEP57 COX5B FAM161B FAM9C INCA1 LENG1 MESD MSGN1 NUP54 OIP5 PPP1R13B SGF29 SMARCE1 SUOX SYCE2 ZNF835
Entrez ID		112869	56158
HPRD ID		13996	12045
Ensembl ID		ENSG00000176476	ENSG00000150783
Uniprot IDs		Q96ES7	Q9BXU0
PDB IDs		3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M	6HK8 6HK9 6R17 6R2F 6YQF
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Tissue Morphogenesis Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Central Element Supramolecular Fiber Organization Hair Cycle Protein-DNA Complex Assembly Synaptonemal Complex Assembly Structural Constituent Of Cytoskeleton Synaptonemal Complex Organization Core Mediator Complex Organelle Organization Anatomical Structure Morphogenesis Protein Binding Spine Apparatus Assembly Mediator Complex
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