SFTPD and DMBT1

Number of citations of the paper that reports this interaction (PMID 9153228)
39

Data Source:
BioGRID (biochemical, pull down, pull down)
HPRD (in vitro)

		SFTPD	DMBT1
Gene Name		surfactant protein D	deleted in malignant brain tumors 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Extracellular Space Lysosome Endocytic Vesicle	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Cytoplasm Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Zymogen Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding	Scavenger Receptor Activity Protein Binding Signaling Pattern Recognition Receptor Activity Zymogen Binding Calcium-dependent Protein Binding
	Biological Process	Regulation Of Cytokine Production Receptor-mediated Endocytosis Respiratory Gaseous Exchange Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Negative Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Reactive Oxygen Species Metabolic Process	Inner Cell Mass Cell Proliferation Pattern Recognition Receptor Signaling Pathway Receptor-mediated Endocytosis Protein Transport Viral Process Epithelial Cell Differentiation Positive Regulation Of Epithelial Cell Differentiation Induction Of Bacterial Agglutination Innate Immune Response Defense Response To Virus
Pathways		Toll Like Receptor 2 (TLR2) Cascade Toll Like Receptor TLR1:TLR2 Cascade Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Signal regulatory protein (SIRP) family interactions Innate Immune System
Drugs		Beta-D-Glucose
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
Protein-Protein Interactions		3 interactors: DCN DMBT1 MFAP4	2 interactors: SFTPA1 SFTPD
Entrez ID		6441	1755
HPRD ID		01522	03575
Ensembl ID		ENSG00000133661	ENSG00000187908
Uniprot IDs		P35247	Q9UGM3
PDB IDs		1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52
Enriched GO Terms of Interacting Partners?		Induction Of Bacterial Agglutination Extracellular Matrix Organization Extracellular Structure Organization Cellular Response To UV-B Elastic Fiber Assembly Response To Bacterium Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Dermatan Sulfate Biosynthetic Process Extracellular Fibril Organization Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Catabolic Process UV Protection Extracellular Matrix Assembly Response To UV-B Response To Other Organism Chondroitin Sulfate Biosynthetic Process Inner Cell Mass Cell Proliferation Response To Biotic Stimulus Chondroitin Sulfate Proteoglycan Biosynthetic Process Antibacterial Humoral Response Antimicrobial Humoral Response Blastocyst Growth Regulation Of Collagen Metabolic Process Peptide Cross-linking Response To Abiotic Stimulus Proteoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Chondroitin Sulfate Metabolic Process Cellular Response To UV Positive Regulation Of Epithelial Cell Differentiation	Respiratory Gaseous Exchange Negative Regulation Of Interleukin-2 Biosynthetic Process Surfactant Homeostasis Chemical Homeostasis Within A Tissue Macrophage Chemotaxis Negative Regulation Of Interleukin-2 Production Regulation Of Interleukin-2 Biosynthetic Process Negative Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Phagocytosis Lung Alveolus Development Negative Regulation Of T Cell Proliferation Regulation Of Phagocytosis Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Leukocyte Chemotaxis Positive Regulation Of Endocytosis Negative Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cytokine Biosynthetic Process Reactive Oxygen Species Metabolic Process Negative Regulation Of Lymphocyte Activation Negative Regulation Of Cell-cell Adhesion
Tagcloud ?			archived cohorts curative ffpe focusing gastric generate generating greatly immunostaining intestinal isoelectric ltf metaplasia metaplasias mucosa neoplastic pathologic polypeptide predominant preneoplastic profiles proteome proteomic spasmolytic stomach tandem uncover worse
Tagcloud (Difference) ?			archived cohorts curative ffpe focusing gastric generate generating greatly immunostaining intestinal isoelectric ltf metaplasia metaplasias mucosa neoplastic pathologic polypeptide predominant preneoplastic profiles proteome proteomic spasmolytic stomach tandem uncover worse
Tagcloud (Intersection) ?