DMBT1 and SFTPD

Number of citations of the paper that reports this interaction (PubMedID 10101009)
0

Data Source:
BioGRID (biochemical, pull down, pull down)
HPRD (in vitro)

		DMBT1	SFTPD
Description		deleted in malignant brain tumors 1	surfactant protein D
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome	Extracellular Region Collagen Trimer Extracellular Space Cytoplasm Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Endocytic Vesicle Clathrin-coated Endocytic Vesicle
	Molecular Function	Lipopolysaccharide Binding DNA Binding Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding Lipoteichoic Acid Binding Heparan Sulfate Binding	Protein Binding Carbohydrate Binding Identical Protein Binding
	Biological Process	Receptor-mediated Endocytosis Defense Response Protein Transport Vesicle-mediated Transport Cell Differentiation Epithelial Cell Differentiation Induction Of Bacterial Agglutination Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Regulation Of Cytokine Production Immune System Process Regulation Of Immune System Process Receptor-mediated Endocytosis Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Reactive Oxygen Species Metabolic Process
Pathways		Surfactant metabolism	Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4 SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs			Beta-D-Glucose
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Iris heterochromicity ( 30895295)	Chronic obstructive pulmonary disease ( 28166215 30804561 33909500) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 24390342 30423114)
Interacting Genes		3 interacting genes: SFTPA1 SFTPD UBC	3 interacting genes: DCN DMBT1 MFAP4
Entrez ID		1755	6441
HPRD ID		03575	01522
Ensembl ID		ENSG00000187908	ENSG00000133661
Uniprot IDs		A0A590UJ76 Q9UGM3	P35247
PDB IDs		6SA4 6SA5 6SAN 8J8D 8J8T 8WZS	1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS
Enriched GO Terms of Interacting Partners?		Respiratory Gaseous Exchange By Respiratory System Clathrin-coated Endocytic Vesicle Extracellular Space Multivesicular Body Collagen Trimer Methanethiol Oxidase Activity	Extracellular Space Extracellular Matrix Extracellular Region Extracellular Matrix Binding
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