HERPUD2 and CYB561A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HERPUD2	CYB561A3
Description		HERPUD family member 2	cytochrome b561 family member A3
Image			No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleolus Lysosome Lysosomal Membrane Endosome Membrane Late Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity
	Biological Process	Response To Unfolded Protein Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response	Intracellular Iron Ion Homeostasis Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Cognitive function ( 24684796) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Essential hypertension (time to event) ( 32589924) Obesity-related traits ( 23251661) PR interval ( 30046033 30679814 32439900)
Interacting Genes		17 interacting genes: ALG10 CYB561A3 EFNA5 IER3IP1 MS4A13 NAF1 RBM11 SLC35A4 SLC39A9 SLC7A1 SPTSSA TAS2R10 TMBIM6 TMEM144 TMEM31 TMEM60 UBE2B	23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31
Entrez ID		64224	220002
HPRD ID		07984	11316
Ensembl ID		ENSG00000122557	ENSG00000162144
Uniprot IDs		Q9BSE4	F5H1Q2 Q8NBI2
PDB IDs		2KDB
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Positive Regulation Of Immune Response Positive Regulation Of Immune Effector Process Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Apicolateral Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Defense Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Alpha-1,2-demannosylation Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Mannose Trimming Endoplasmic Reticulum Quality Control Compartment Protein Deglycosylation Bicellular Tight Junction Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Diamine Oxidase Activity Putrescine Oxidase Activity Histamine Oxidase Activity Nitrate Transmembrane Transporter Activity Regulation Of Immune Response Immune Response-activating Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Inhibitory MHC Class Ib Receptor Activity B Cell Proliferation G Protein-coupled Receptor Activity Plasma Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Immune System Process Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Activation Of Immune Response Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Innate Immune Response-activating Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Regulation Of Innate Immune Response Activation Of Innate Immune Response Regulation Of Acute Inflammatory Response HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Receptor Complex Regulation Of T Cell Mediated Cytotoxicity
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