CDH23 and USH1C

Number of citations of the paper that reports this interaction (PMID 12485990)
106

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		CDH23	USH1C
Gene Name		cadherin-related 23	Usher syndrome 1C (autosomal recessive, severe)
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Stereocilium	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Cytosol Cytoskeleton Plasma Membrane Brush Border Stereocilium Apical Part Of Cell Synapse
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding Spectrin Binding Myosin Tail Binding Actin Filament Binding
	Biological Process	Calcium Ion Transport Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Visual Perception Sensory Perception Of Sound Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Photoreceptor Cell Maintenance Response To Stimulus Sensory Perception Of Light Stimulus Equilibrioception Cytosolic Calcium Ion Homeostasis	G2/M Transition Of Mitotic Cell Cycle Sensory Perception Of Sound Parallel Actin Filament Bundle Assembly Inner Ear Morphogenesis Auditory Receptor Cell Differentiation Photoreceptor Cell Maintenance Sensory Perception Of Light Stimulus Equilibrioception
Pathways
Drugs
Diseases
GWAS		Vitiligo ( 22951725)
Protein-Protein Interactions		2 interactors: MYO7A USH1C	9 interactors: ANKS4B CDH23 CTNNAL1 MIPOL1 MYO7A QKI RAC1 USH1G USHBP1
Entrez ID		64072	10083
HPRD ID		05699	09241
Ensembl ID		ENSG00000107736	ENSG00000006611
Uniprot IDs		A5D6V9 Q6P152 Q8N5B3 Q9H251	Q9Y6N9
PDB IDs		2KBR 2KBS 2LSR	1X5N 2KBQ 2KBR 2KBS 2LSR 3K1R
Enriched GO Terms of Interacting Partners?		Equilibrioception Auditory Receptor Cell Differentiation Hair Cell Differentiation Inner Ear Receptor Cell Differentiation Mechanoreceptor Differentiation Neuromuscular Process Controlling Balance Inner Ear Morphogenesis Ear Morphogenesis Neuromuscular Process Epidermal Cell Differentiation Sensory Perception Of Sound Sensory Perception Of Light Stimulus Sensory Perception Of Mechanical Stimulus Inner Ear Development Ear Development Epidermis Development Parallel Actin Filament Bundle Assembly Embryonic Organ Morphogenesis Embryonic Organ Development Epithelial Cell Differentiation Sensory Organ Development Post-embryonic Organ Morphogenesis Auditory Receptor Cell Stereocilium Organization Embryonic Morphogenesis Actin Filament-based Process Auditory Receptor Cell Morphogenesis Phagolysosome Assembly Sensory Perception Auditory Receptor Cell Development Inner Ear Receptor Stereocilium Organization Organ Morphogenesis Epithelium Development Neuron Differentiation Embryo Development Neurological System Process Photoreceptor Cell Maintenance Pigment Granule Transport Eye Photoreceptor Cell Development Inner Ear Receptor Cell Development Phagosome Maturation Photoreceptor Cell Development Eye Photoreceptor Cell Differentiation Generation Of Neurons Lysosome Organization Neurogenesis Retina Homeostasis Cellular Pigmentation Actin Filament-based Movement Tissue Development Actin Filament Bundle Assembly	Equilibrioception Inner Ear Receptor Cell Differentiation Mechanoreceptor Differentiation Neuromuscular Process Controlling Balance Inner Ear Morphogenesis Ear Morphogenesis Auditory Receptor Cell Morphogenesis Neuromuscular Process Sensory Perception Of Sound Auditory Receptor Cell Development Sensory Perception Of Light Stimulus Tissue Homeostasis Sensory Perception Of Mechanical Stimulus Inner Ear Development Ear Development Multicellular Organismal Homeostasis Auditory Receptor Cell Differentiation Photoreceptor Cell Maintenance Hair Cell Differentiation Inner Ear Receptor Cell Development Embryonic Organ Morphogenesis Retina Homeostasis Embryonic Organ Development Sensory Organ Development Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production 3'-UTR-mediated MRNA Destabilization Embryonic Morphogenesis Epidermal Cell Differentiation Engulfment Of Apoptotic Cell Visual Perception Mast Cell Chemotaxis Sensory Perception Epithelial Cell Development MRNA Destabilization Tangential Migration From The Subventricular Zone To The Olfactory Bulb Organ Morphogenesis Nervous System Development Post-embryonic Organ Morphogenesis Phagocytosis Epidermis Development Olfactory Bulb Interneuron Development Auditory Receptor Cell Stereocilium Organization Anatomical Structure Morphogenesis Regulation Of Hydrogen Peroxide Metabolic Process RNA Destabilization Neuron Differentiation Embryo Development Regulation Of Respiratory Burst Neurological System Process
Tagcloud ?		alters annotation ca3 candidate dataset disequilibrium ear fdr filtering gwas harbored hist3h3 hypotheses hypothetical icsnpathway il27ra innate modulates morphogenesis pneumoconiosis ptprz1 rs11592462 rs2230656 rs2292151 rs8120 snps stereocilia strongest ticam1
Tagcloud (Difference) ?		alters annotation ca3 candidate dataset disequilibrium ear fdr filtering gwas harbored hist3h3 hypotheses hypothetical icsnpathway il27ra innate modulates morphogenesis pneumoconiosis ptprz1 rs11592462 rs2230656 rs2292151 rs8120 snps stereocilia strongest ticam1
Tagcloud (Intersection) ?