NICN1 and TRAPPC2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		NICN1	TRAPPC2B
Description		nicolin 1, tubulin polyglutamylase complex subunit	trafficking protein particle complex subunit 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Microtubule	Nucleus Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex
	Molecular Function	Protein Binding	Transcription Corepressor Binding Protein Binding Transcription Regulator Inhibitor Activity
	Biological Process		Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Positive Regulation Of Gene Expression Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Mood instability ( 31168069) Red cell distribution width ( 28957414) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: ATP6V0D2 NFKBID P4HA3 POGZ RUSC1 TENT5B TLX3 TRAPPC2 TRAPPC2B TTC9C ZNF77	19 interacting genes: EPS15L1 INCA1 JOSD2 KCTD1 LSM3 MBD3L1 NICN1 NME4 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC5 TRIM42 UQCC2 ZBED1 ZNF438 ZNF655 ZRANB1
Entrez ID		84276	10597
HPRD ID		17631
Ensembl ID		ENSG00000145029	ENSG00000256060
Uniprot IDs		Q9BSH3	P0DI82
PDB IDs
Enriched GO Terms of Interacting Partners?		TRAPPII Protein Complex TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Vesicle Tethering Vesicle Coating Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Proton-transporting V-type ATPase Complex	TRAPPII Protein Complex TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Deubiquitinase Activity Vesicle Tethering Intermembrane Phospholipid Transfer Protein Autosumoylation Vesicle Coating TRAPPI Protein Complex Coated Vesicle Membrane
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