SCN2B and SCN1B

Number of citations of the paper that reports this interaction (PMID 6319405)
49

Data Source:
HPRD (in vivo)

		SCN2B	SCN1B
Gene Name		sodium channel, voltage gated, type II beta subunit	sodium channel, voltage gated, type I beta subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Voltage-gated Sodium Channel Complex	Voltage-gated Sodium Channel Complex Extracellular Region Intercalated Disc T-tubule Node Of Ranvier
	Molecular Function	Sodium Channel Regulator Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential	Voltage-gated Sodium Channel Activity Sodium Channel Regulator Activity Sodium Channel Inhibitor Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Voltage-gated Sodium Channel Activity Involved In Purkinje Myocyte Action Potential
	Biological Process	Synaptic Transmission Nervous System Development Sodium Ion Transmembrane Transport Response To Pyrethroid Cardiac Muscle Contraction Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Cardiac Muscle Cell Action Potential Involved In Contraction Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Cell Adhesion Synaptic Transmission Axon Guidance Positive Regulation Of Sodium Ion Transport Positive Regulation Of Neuron Projection Development Neuronal Action Potential Propagation Corticospinal Neuron Axon Guidance Sodium Ion Transmembrane Transport Locomotion Response To Pyrethroid Membrane Depolarization Cardiac Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Membrane Depolarization During Cardiac Muscle Cell Action Potential Membrane Depolarization During Purkinje Myocyte Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions	Interaction between L1 and Ankyrins Axon guidance L1CAM interactions
Drugs
Diseases
GWAS		Preeclampsia ( 23551011)	Serum albumin level ( 23022100)
Protein-Protein Interactions		1 interactors: SCN1B	3 interactors: ANK3 NFASC SCN2B
Entrez ID		6327	6324
HPRD ID		03208	02581
Ensembl ID		ENSG00000149575	ENSG00000105711
Uniprot IDs		O60939 Q5U0K8	B4DI92 Q07699
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Depolarization During Purkinje Myocyte Cell Action Potential Corticospinal Neuron Axon Guidance Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Response To Pyrethroid Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Neuronal Action Potential Propagation Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cell-cell Signaling Involved In Cardiac Conduction Corticospinal Tract Morphogenesis Response To Insecticide Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Membrane Depolarization During Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Depolarization Cardiac Muscle Cell Action Potential Positive Regulation Of Sodium Ion Transport Central Nervous System Projection Neuron Axonogenesis Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cardiac Muscle Contraction Transmission Of Nerve Impulse Heart Contraction Central Nervous System Neuron Axonogenesis Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Central Nervous System Neuron Development Membrane Depolarization Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Muscle Contraction Regulation Of Ion Homeostasis Regulation Of Heart Contraction Response To Toxic Substance Positive Regulation Of Ion Transport Sodium Ion Transmembrane Transport Muscle Contraction Central Nervous System Neuron Differentiation Positive Regulation Of Neuron Projection Development Sodium Ion Transport Muscle System Process Regulation Of Membrane Potential Positive Regulation Of Cell Projection Organization	Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Membrane Depolarization Regulation Of Sodium Ion Transmembrane Transport Transmission Of Nerve Impulse Regulation Of Sodium Ion Transport Action Potential Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Maintenance Of Protein Location In Plasma Membrane Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Ion Homeostasis Synapse Organization Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Membrane Potential Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Cellular Response To Magnesium Ion Response To Pyrethroid Regulation Of Membrane Depolarization During Action Potential Axon Guidance Clustering Of Voltage-gated Sodium Channels Regulation Of Cardiac Muscle Cell Action Potential Nervous System Development Regulation Of Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Action Potential Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Cell Communication By Electrical Coupling Neuronal Ion Channel Clustering Protein Localization To Paranode Region Of Axon Cytoskeletal Anchoring At Plasma Membrane Protein Localization To Juxtaparanode Region Of Axon Axonogenesis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Membrane Depolarization During Cardiac Muscle Cell Action Potential Axon Development Negative Regulation Of Potassium Ion Transmembrane Transport Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Ion Transport Magnesium Ion Homeostasis Paranodal Junction Assembly Neuron Projection Morphogenesis Response To Insecticide Response To Magnesium Ion Negative Regulation Of Cation Channel Activity Cell Morphogenesis Involved In Differentiation Heterotypic Cell-cell Adhesion
Tagcloud ?			adam19 atria conduction connexins coq7 cx40 dyrk1a electrocardiogram f5 gabpa hmgn1 lethality monosomic morc3 ms5yah natal ncx1 pde10a pinpoint precordial scn10a scn5a slc5a3 slc8a1 tfb1m tiam1 trisomic ts65dn ventricles
Tagcloud (Difference) ?			adam19 atria conduction connexins coq7 cx40 dyrk1a electrocardiogram f5 gabpa hmgn1 lethality monosomic morc3 ms5yah natal ncx1 pde10a pinpoint precordial scn10a scn5a slc5a3 slc8a1 tfb1m tiam1 trisomic ts65dn ventricles
Tagcloud (Intersection) ?