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RPS13 and NFKB2
Number of citations of the paper that reports this interaction (PMID
14743216
)
197
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro)
RPS13
NFKB2
Gene Name
ribosomal protein S13
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Cytosol
Ribosome
Focal Adhesion
Membrane
Cytosolic Small Ribosomal Subunit
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Bcl3/NF-kappaB2 Complex
Molecular Function
MRNA Binding
Structural Constituent Of Ribosome
Protein Binding
Poly(A) RNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Coactivator Activity
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Initiation
Translational Elongation
Translational Termination
SRP-dependent Cotranslational Protein Targeting To Membrane
Gene Expression
Viral Process
Viral Life Cycle
Viral Transcription
Negative Regulation Of RNA Splicing
Cellular Protein Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Toll-like Receptor Signaling Pathway
Follicular Dendritic Cell Differentiation
Germinal Center Formation
MyD88-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Inflammatory Response
I-kappaB Kinase/NF-kappaB Signaling
Extracellular Matrix Organization
Positive Regulation Of Type I Interferon Production
Response To Cytokine
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Innate Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Rhythmic Process
Spleen Development
Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Nonsense-Mediated Decay (NMD)
Translation initiation complex formation
Translation
SRP-dependent cotranslational protein targeting to membrane
Eukaryotic Translation Termination
Peptide chain elongation
Influenza Infection
Viral mRNA Translation
L13a-mediated translational silencing of Ceruloplasmin expression
Influenza Life Cycle
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Ribosomal scanning and start codon recognition
Formation of the ternary complex, and subsequently, the 43S complex
Influenza Viral RNA Transcription and Replication
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Initiation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Formation of a pool of free 40S subunits
Eukaryotic Translation Elongation
Cap-dependent Translation Initiation
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Toll Like Receptor 7/8 (TLR7/8) Cascade
RIP-mediated NFkB activation via ZBP1
Toll Like Receptor TLR6:TLR2 Cascade
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
ZBP1(DAI) mediated induction of type I IFNs
MyD88 dependent cascade initiated on endosome
MyD88:Mal cascade initiated on plasma membrane
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Toll Like Receptor 9 (TLR9) Cascade
Innate Immune System
TRIF-mediated TLR3/TLR4 signaling
Cytosolic sensors of pathogen-associated DNA
Cytokine Signaling in Immune system
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Toll-Like Receptors Cascades
Signaling by Interleukins
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
Interleukin-1 processing
TRAF6 mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
MAP3K14
NFKB2
PDCD4
SPP1
35 interactors:
BCL3
BTRC
CHUK
DDX3X
DPF2
EPS8
GLG1
GTF2I
HDAC4
HDAC5
IKBKB
IKBKG
MAP3K14
MAP3K8
MEN1
NFKB1
NFKBIA
NFKBIB
NFKBIE
NFKBIZ
NKRF
NR3C1
NR5A1
PSMD11
REL
RELA
RELB
RPL30
RPL6
RPS13
SIN3A
SP1
TNIP2
TSC22D3
USP2
Entrez ID
6207
4791
HPRD ID
01604
01239
Ensembl ID
ENSG00000110700
ENSG00000077150
Uniprot IDs
P62277
Q00653
PDB IDs
3J3A
1A3Q
2D96
3DO7
Enriched GO Terms of Interacting Partners
?
NIK/NF-kappaB Signaling
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Follicular Dendritic Cell Differentiation
Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Regulation Of MAP Kinase Activity
Negative Regulation Of Collateral Sprouting
Negative Regulation Of Axon Regeneration
Extracellular Matrix Organization
Extracellular Structure Organization
Positive Regulation Of Cell Adhesion
Inflammatory Response
Negative Regulation Of JUN Kinase Activity
Germinal Center Formation
Positive Regulation Of Bone Resorption
Immune System Process
Regulation Of Axon Regeneration
Regulation Of MAPK Cascade
Regulation Of Cell Adhesion
Positive Regulation Of Tissue Remodeling
Decidualization
Response To Vitamin D
Negative Regulation Of JNK Cascade
Regulation Of Protein Kinase Activity
Negative Regulation Of Stress-activated MAPK Cascade
Regulation Of Bone Resorption
I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Immune System Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Toll-like Receptor 3 Signaling Pathway
Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Type I Interferon Production
Activation Of Innate Immune Response
Gene Expression
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Toll-like Receptor 5 Signaling Pathway
RNA Metabolic Process
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Type I Interferon Production
Toll-like Receptor Signaling Pathway
Transcription, DNA-templated
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
MyD88-independent Toll-like Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Inflammatory Response
Pattern Recognition Receptor Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
NIK/NF-kappaB Signaling
Macromolecule Biosynthetic Process
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Innate Immune Response
Positive Regulation Of Cytokine Production
Negative Regulation Of Gene Expression
Intracellular Signal Transduction
Tagcloud
?
arrangement
bcl
cbcl
cbcls
clonal
clonality
cls
ctcl
ctcls
cutaneous
deletions
extranodal
germline
hodgkin
ig
lymphoid
lymphomas
lyt
malignancies
neoplasias
nodal
oncogenes
pathogenetic
rearrangement
rearrangements
southern
tal
tcr
undetectable
Tagcloud (Difference)
?
arrangement
bcl
cbcl
cbcls
clonal
clonality
cls
ctcl
ctcls
cutaneous
deletions
extranodal
germline
hodgkin
ig
lymphoid
lymphomas
lyt
malignancies
neoplasias
nodal
oncogenes
pathogenetic
rearrangement
rearrangements
southern
tal
tcr
undetectable
Tagcloud (Intersection)
?