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RPS13 and NFKB2
Number of citations of the paper that reports this interaction (PubMedID
14743216
)
0
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro)
RPS13
NFKB2
Description
ribosomal protein S13
nuclear factor kappa B subunit 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Ribosome
Focal Adhesion
Postsynaptic Density
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Small-subunit Processome
Extracellular Exosome
Ribonucleoprotein Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
I-kappaB/NF-kappaB Complex
Bcl3/NF-kappaB2 Complex
Molecular Function
RNA Binding
MRNA Binding
Structural Constituent Of Ribosome
Protein Binding
MRNA 5'-UTR Binding
Small Ribosomal Subunit RRNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Cytoplasmic Translation
Translation
Negative Regulation Of RNA Splicing
Ribosomal Small Subunit Biogenesis
Follicular Dendritic Cell Differentiation
Germinal Center Formation
Regulation Of DNA-templated Transcription
Signal Transduction
Canonical NF-kappaB Signal Transduction
Extracellular Matrix Organization
Response To Lipopolysaccharide
Response To Cytokine
Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Spleen Development
Intracellular Signaling Cassette
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
RIP-mediated NFkB activation via ZBP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
PKMTs methylate histone lysines
TAK1-dependent IKK and NF-kappa-B activation
Interleukin-1 processing
SUMOylation of immune response proteins
IkBA variant leads to EDA-ID
Dectin-1 mediated noncanonical NF-kB signaling
NIK-->noncanonical NF-kB signaling
The NLRP3 inflammasome
TRAF6 mediated NF-kB activation
Purinergic signaling in leishmaniasis infection
Regulation of PD-L1(CD274) transcription
Drugs
Artenimol
Sulfasalazine
Donepezil
Pranlukast
HE3286
P54
NOX-700
SGN-30
Custirsen
NF-kappaB Decoy
Andrographolide
Terpinen-4-ol
Glycyrrhizic acid
Fish oil
SC-236
Diseases
GWAS
Body mass index (
26426971
)
Smoking status (ever vs never smokers) (
30643258
)
Metabolite levels (
23823483
)
Refractive error (
32231278
)
Ulcerative colitis (
26192919
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
9 interacting genes:
CLIP4
DUX4
MAP3K14
NFKB2
PDCD4
PPIL3
PTEN
RBFOX2
SPP1
36 interacting genes:
BCL3
BTRC
CHUK
DDX3X
DPF2
EPS8
GLG1
GTF2I
HDAC4
HDAC5
IKBKB
IKBKG
MAP3K14
MAP3K8
MEN1
MTDH
NFKB1
NFKBIA
NFKBIB
NFKBIE
NFKBIZ
NKRF
NR3C1
NR5A1
PSMD11
REL
RELA
RELB
RPL30
RPL6
RPS13
SIN3A
SP1
TNIP2
TSC22D3
USP2
Entrez ID
6207
4791
HPRD ID
01604
01239
Ensembl ID
ENSG00000110700
ENSG00000077150
Uniprot IDs
P62277
Q00653
PDB IDs
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G18
6G4S
6G4W
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBD
6YBW
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOK
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7JQB
7JQC
7K5I
7MQ8
7MQ9
7MQA
7QP6
7QP7
7R4X
7TQL
7WTS
7WTT
7WTU
7WTV
7WTW
7WTX
7WTZ
7WU0
7XNX
7XNY
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8RG0
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
1A3Q
2D96
3DO7
4OT9
5ZMC
7CLI
7VUP
7VUQ
7W7L
8G8Q
8G8S
Enriched GO Terms of Interacting Partners
?
Non-canonical NF-kappaB Signal Transduction
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Bcl3/NF-kappaB2 Complex
I-kappaB/NF-kappaB Complex
Follicular Dendritic Cell Activation
Follicular Dendritic Cell Differentiation
Negative Regulation Of Synaptic Vesicle Clustering
Negative Regulation Of Axonogenesis
Negative Regulation Of Developmental Growth
Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity
Negative Regulation Of Keratinocyte Migration
Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity
Negative Regulation Of Smooth Muscle Cell Proliferation
Central Nervous System Myelin Maintenance
Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Protein Phosphorylation
Rhythmic Synaptic Transmission
Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Positive Regulation Of Estradiol Secretion
Regulation Of Estradiol Secretion
Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development
Negative Regulation Of Phosphorylation
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Neuron Projection Development
Osteoblast Differentiation
Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells
Negative Regulation Of Neurogenesis
Regulation Of Axonogenesis
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
Myelin Sheath Adaxonal Region
Negative Regulation Of Nervous System Development
Regulation Of Smooth Muscle Cell Proliferation
Phosphatidylinositol Phosphate Phosphatase Activity
Androgen Catabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Synaptic Vesicle Clustering
Negative Regulation Of Phosphate Metabolic Process
Negative Regulation Of Myofibroblast Differentiation
Negative Regulation Of Peptidyl-serine Phosphorylation
Postsynaptic Density Assembly
Regulation Of Response To Wounding
Cellular Response To Testosterone Stimulus
Negative Regulation Of G0 To G1 Transition
Negative Regulation Of Cell Projection Organization
Regulation Of Nucleobase-containing Compound Metabolic Process
Neuron-neuron Synaptic Transmission
Negative Regulation Of Cell Differentiation
Negative Regulation Of Cell Size
Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Canonical NF-kappaB Signal Transduction
Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Inflammatory Response
Regulation Of Gene Expression
Immune System Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Defense Response
Intracellular Signaling Cassette
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Metabolic Process
Activation Of Immune Response
Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Macromolecule Biosynthetic Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Nucleus
Response To External Biotic Stimulus
Immune Response-activating Signaling Pathway
Negative Regulation Of Biosynthetic Process
Cytoplasm
Intracellular Signal Transduction
Regulation Of Metabolic Process
Regulation Of DNA-binding Transcription Factor Activity
Nucleoplasm
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Activation Of Innate Immune Response
Response To Stress
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Signal Transduction
Positive Regulation Of Defense Response
NF-kappaB Complex
Pattern Recognition Receptor Signaling Pathway
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
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