RPL9 and BICDL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPL9	BICDL2
Description		ribosomal protein L9	BICD family like cargo adaptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding	Protein Binding Small GTPase Binding
	Biological Process	Cytoplasmic Translation Translation	Vesicle Transport Along Microtubule Golgi To Secretory Granule Transport
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258)
Interacting Genes		39 interacting genes: BACH2 BICDL2 CALCOCO2 CBY2 CCDC184 CEBPA CEP76 CTTN DHPS DRAP1 DUX4 ESR1 FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 OGT PNMA2 PPP1R27 PSTPIP1 QKI RALY RPS3 SNRPF SORBS2 SREK1IP1 SRSF3 STAC3 SUPT5H TIFA TNFAIP8L1 TRIM37 UBALD1 USO1 ZBTB14 ZBTB7B ZBTB8A	7 interacting genes: API5 CDK17 CFTR KLC3 PKP1 RPL9 TSGA10IP
Entrez ID		6133	146439
HPRD ID		04732	11237
Ensembl ID		ENSG00000163682	ENSG00000162069
Uniprot IDs		P32969 Q53Z07	A1A5D9
PDB IDs		2CQL 4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7QVP 7XNX 7XNY 8A3D 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Binding	Transepithelial Water Transport Epithelial Fluid Transport Water Transport Fluid Transport Transepithelial Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Anion Channel Activity Desmosome Maintenance Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Intermediate Filament Binding Positive Regulation Of Cytoplasmic Translational Initiation Nuclear Stress Granule Ameloblast Differentiation Intermediate Filament Bundle Assembly Desmosome Assembly Negative Regulation Of Fibroblast Apoptotic Process Sperm Mitochondrial Sheath Assembly Amelogenesis Ciliary Rootlet ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Fibroblast Apoptotic Process
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