ARL3 and RP2

Number of citations of the paper that reports this interaction (PMID 11847227)
22

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		ARL3	RP2
Gene Name		ADP-ribosylation factor-like 3	retinitis pigmentosa 2 (X-linked recessive)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Midbody Photoreceptor Connecting Cilium Extracellular Vesicular Exosome Primary Cilium	Cytoplasm Golgi Apparatus Centriole Plasma Membrane Cytoplasmic Vesicle Ciliary Basal Body Extracellular Vesicular Exosome Primary Cilium Periciliary Membrane Compartment
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Metal Ion Binding	Actin Binding Nucleoside Diphosphate Kinase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Unfolded Protein Binding
	Biological Process	Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Organelle Organization Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Protein Transport Intraciliary Transport Photoreceptor Cell Development Cilium Morphogenesis	Cell Morphogenesis Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Protein Folding Post-Golgi Vesicle-mediated Transport Organelle Organization Cytoskeleton Organization Post-chaperonin Tubulin Folding Pathway Visual Perception Protein Transport Positive Regulation Of GTPase Activity
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Trafficking of myristoylated proteins to the cilium Assembly of the primary cilium	Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Trafficking of myristoylated proteins to the cilium Assembly of the primary cilium
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		10 interactors: ARL2BP GOLGA4 LRIF1 PDE6D RP2 TLE1 TP53 TUBA1A UBR1 UNC119	1 interactors: ARL3
Entrez ID		403	6102
HPRD ID		05260	02424
Ensembl ID		ENSG00000138175	ENSG00000102218
Uniprot IDs		P36405	O75695
PDB IDs			2BX6 3BH6 3BH7
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Peptidyl-tyrosine Phosphorylation Visual Perception Sensory Perception Of Light Stimulus Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Clathrin-mediated Endocytosis Regulation Of Cellular Amino Acid Metabolic Process Protein Localization Post-Golgi Vesicle-mediated Transport Negative Regulation Of Macromitophagy Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Oligodendrocyte Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Protein Localization To Organelle Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Notch Signaling Pathway Regulation Of Catalytic Activity Cellular Localization Protein Transport Protein Localization To Nucleus Establishment Of Protein Localization Mitotic Cell Cycle Process Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Intracellular Transport Mitochondrial DNA Repair Response To Leucine Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Phosphorylation Mitotic Cell Cycle Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Mitotic Cytokinetic Process Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence Sensory Perception Regulation Of Intracellular Signal Transduction ER Overload Response Positive Regulation Of Phosphorylation Negative Regulation Of Macroautophagy Stress-induced Premature Senescence	Intraciliary Transport Photoreceptor Cell Development Post-Golgi Vesicle-mediated Transport Cytokinesis Smoothened Signaling Pathway Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport
Tagcloud ?		accord brucei congolense conservation cruzi donovani eukaryotes flanking genesis leishmania monophyly multigene organization parasites phylogeny primitive protozoan rab1 reconstitution representatives s12 salivarian transporter trypanosoma trypanosomatids trypanosomes unicellular vivax ypt6	challenges combinations consequences deal dichotomized diphosphate displaying face great hetero hexamers highlight motility ndpk ndpks nm23 nme nme1 nmes nucleoside oligomers perhaps redundancy span spread surprising taxonomically typically uncertainty
Tagcloud (Difference) ?		accord brucei congolense conservation cruzi donovani eukaryotes flanking genesis leishmania monophyly multigene organization parasites phylogeny primitive protozoan rab1 reconstitution representatives s12 salivarian transporter trypanosoma trypanosomatids trypanosomes unicellular vivax ypt6	challenges combinations consequences deal dichotomized diphosphate displaying face great hetero hexamers highlight motility ndpk ndpks nm23 nme nme1 nmes nucleoside oligomers perhaps redundancy span spread surprising taxonomically typically uncertainty
Tagcloud (Intersection) ?