HORMAD1 and MSL1

Number of citations of the paper that reports this interaction (PubMedID 19650074)
0

Data Source:
BioGRID (two hybrid)

		HORMAD1	MSL1
Description		HORMA domain containing 1	MSL complex subunit 1
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GO Annotations	Cellular Component	Condensed Nuclear Chromosome Synaptonemal Complex Nucleus Chromosome	Nucleus Nucleoplasm Nuclear Speck MSL Complex
	Molecular Function	Protein Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Blastocyst Development Homologous Chromosome Pairing At Meiosis Synaptonemal Complex Assembly Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Sister Chromatid Cohesion Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling Regulation Of Homologous Chromosome Segregation	Chromatin Organization Chromatin Remodeling Positive Regulation Of DNA-templated Transcription
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) Rhegmatogenous retinal detachment ( 23585552) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Asthma ( 31619474)
Interacting Genes		4 interacting genes: BRCA1 MEOX2 MSL1 MYG1	17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3
Entrez ID		84072	339287
HPRD ID		11396	19425
Ensembl ID		ENSG00000143452	ENSG00000188895
Uniprot IDs		A0A140VKG9 Q86X24	B3KWR7 J3KSZ8 J3QQY0 Q68DK7
PDB IDs		8J69	4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Centrosome Duplication Negative Regulation Of Centriole Replication BRCA1-A Complex XY Body BRCA1-B Complex Histone H2AK127 Ubiquitin Ligase Activity Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Lateral Element Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol Positive Regulation Of RNA Biosynthetic Process BRCA1-C Complex Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Gamma-tubulin Ring Complex Ubiquitin-modified Histone Reader Activity Histone H2AK129 Ubiquitin Ligase Activity Positive Regulation Of DNA-templated Transcription Response To Indole-3-methanol DNA Strand Resection Involved In Replication Fork Processing BRCA1-BARD1 Complex DNA Repair Complex Random Inactivation Of X Chromosome Nuclear Speck Segment Specification Somite Development Somite Specification Locomotory Exploration Behavior MSL Complex RNA Polymerase Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process	Nucleoplasm Regulation Of Cell Cycle Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Import Into Nucleus Chromatin Binding HULC Complex Positive Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Importin-alpha Family Protein Binding Positive Regulation Of Biosynthetic Process Chromatin Organization Positive Regulation Of Double-strand Break Repair Transcription Coactivator Activity Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process NuA4 Histone Acetyltransferase Complex Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Metabolic Process Protein Localization To Nucleus Fibroblast Proliferation Reproductive Structure Development Negative Regulation Of Protein Kinase C Signaling Regulation Of Nucleobase-containing Compound Metabolic Process Stereocilium Shaft Positive Regulation Of Double-strand Break Repair Via Homologous Recombination H4/H2A Histone Acetyltransferase Complex Histone H2B C-terminal K Residue Ubiquitin Ligase Activity Regulation Of Macromolecule Metabolic Process Male Germ Cell Nucleus Developmental Process Involved In Reproduction Regulation Of DNA Repair Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Response To Stress Helper T Cell Diapedesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Ubiquitin-protein Transferase Activity Regulation Of Primary Metabolic Process
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