RLBP1 and RDH5

Number of citations of the paper that reports this interaction (PMID 12536149)
2

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RLBP1	RDH5
Gene Name		retinaldehyde binding protein 1	retinol dehydrogenase 5 (11-cis/9-cis)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytosol Cell Body	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cell Body
	Molecular Function	Transporter Activity 11-cis Retinal Binding Retinol Binding	Retinol Dehydrogenase Activity
	Biological Process	Retinoid Metabolic Process Vitamin A Metabolic Process Transport Visual Perception Phototransduction, Visible Light	Retinoid Metabolic Process Visual Perception Phototransduction, Visible Light Retinol Metabolic Process Oxidation-reduction Process
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction The retinoid cycle in cones (daylight vision)	Visual phototransduction Signaling by Retinoic Acid The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction RA biosynthesis pathway
Drugs		Vitamin A	NADH Vitamin A
Diseases
GWAS			Refractive error ( 23396134)
Protein-Protein Interactions		3 interactors: APP RDH5 SLC9A3R1	2 interactors: RGR RLBP1
Entrez ID		6017	5959
HPRD ID		01572	03370
Ensembl ID		ENSG00000140522	ENSG00000135437
Uniprot IDs		P12271	Q92781
PDB IDs		1XGG 1XGH 3HX3 3HY5
Enriched GO Terms of Interacting Partners?		Renal Phosphate Ion Absorption Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Renal Sodium Ion Transport Axon Midline Choice Point Recognition Response To Light Stimulus Alcohol Metabolic Process Cellular Phosphate Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Response To Radiation Cellular Ion Homeostasis Neuron Remodeling Bile Acid Secretion Oligopeptide Transport Cellular Chemical Homeostasis Negative Regulation Of Sodium Ion Transport Renal Absorption Regulation Of Proton Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Phosphate Ion Homeostasis Ion Homeostasis Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Assembly Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Secretion Cellular Copper Ion Homeostasis Cellular Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Regulation Of Excretion Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Retinol Metabolic Process Regulation Of Kinase Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Chemical Homeostasis Bile Acid And Bile Salt Transport	Phototransduction Detection Of Light Stimulus Visual Perception Detection Of Abiotic Stimulus Sensory Perception Of Light Stimulus Response To Light Stimulus Response To Radiation Detection Of Stimulus Vitamin A Metabolic Process Protein-chromophore Linkage Sensory Perception Response To Abiotic Stimulus Neurological System Process Chemokine-mediated Signaling Pathway Response To External Stimulus Phototransduction, Visible Light Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Vitamin Metabolic Process Isoprenoid Metabolic Process
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