RDH5 and RGR

Number of citations of the paper that reports this interaction (PMID 11274198)
9

Data Source:
HPRD (in vivo)

		RDH5	RGR
Gene Name		retinol dehydrogenase 5 (11-cis/9-cis)	retinal G protein coupled receptor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cell Body	Integral Component Of Plasma Membrane
	Molecular Function	Retinol Dehydrogenase Activity	G-protein Coupled Receptor Activity Chemokine Receptor Activity Protein Binding Photoreceptor Activity
	Biological Process	Retinoid Metabolic Process Visual Perception Phototransduction, Visible Light Retinol Metabolic Process Oxidation-reduction Process	Chemotaxis G-protein Coupled Receptor Signaling Pathway Visual Perception Phototransduction Protein-chromophore Linkage Chemokine-mediated Signaling Pathway
Pathways		Visual phototransduction Signaling by Retinoic Acid The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction RA biosynthesis pathway	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) Opsins G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		NADH Vitamin A
Diseases
GWAS		Refractive error ( 23396134)
Protein-Protein Interactions		2 interactors: RGR RLBP1	2 interactors: KIAA1279 RDH5
Entrez ID		5959	5995
HPRD ID		03370	02642
Ensembl ID		ENSG00000135437
Uniprot IDs		Q92781	P47804
PDB IDs
Enriched GO Terms of Interacting Partners?		Phototransduction Detection Of Light Stimulus Visual Perception Detection Of Abiotic Stimulus Sensory Perception Of Light Stimulus Response To Light Stimulus Response To Radiation Detection Of Stimulus Vitamin A Metabolic Process Protein-chromophore Linkage Sensory Perception Response To Abiotic Stimulus Neurological System Process Chemokine-mediated Signaling Pathway Response To External Stimulus Phototransduction, Visible Light Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Vitamin Metabolic Process Isoprenoid Metabolic Process
Tagcloud ?			autonomous bipartite carboxyl coincident corrects cos dnaj foci grs hdj hsdj hsp70 inappropriate localizes misfolded mistargeting mobilized nls nlss pnls possessing proto r496 reflecting refolding rgrs rgs subnuclear transrepression
Tagcloud (Difference) ?			autonomous bipartite carboxyl coincident corrects cos dnaj foci grs hdj hsdj hsp70 inappropriate localizes misfolded mistargeting mobilized nls nlss pnls possessing proto r496 reflecting refolding rgrs rgs subnuclear transrepression
Tagcloud (Intersection) ?