HIVEP2 and RFX1

Number of citations: 44 (PubMedID 10642512)
Data Source: HPRD (in vivo)

		HIVEP2	RFX1
Name		HIVEP zinc finger 2	regulatory factor X1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Immune Response
GWAS		Adiponectin levels ( 24105470 ) Adult body size ( 32376654 ) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686 ) Age at first birth ( 34211149 ) Asthma ( 32296059 ) Bipolar disorder ( 31043756 ) Coronary artery disease ( 29212778 ) Daytime sleep phenotypes ( 27126917 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Gastroesophageal reflux disease ( 34187846 ) HDL cholesterol levels ( 32203549 ) Hemoglobin ( 32888494 ) IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391 ) Mood instability ( 31168069 ) Pit-and-Fissure caries ( 24556642 ) Platelet distribution width ( 32888494 ) Type 2 diabetes ( 32499647 ) Weight ( 28552196 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: PAX6	1 novel interactors: PRKACA
Interacting Genes		8 interacting genes: BRWD1 BTG3 CREBBP LINC01554 MTNR1A RFX1 RSPH1 YWHAE	14 interacting genes: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3
Entrez ID		3097	5989
HPRD ID		00881	02476
Ensembl ID		ENSG00000010818	ENSG00000132005
Uniprot IDs		P31629	P22670
PDB IDs		Not available	1DP7
GO Terms Enriched among Interactors		None	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Heteromeric SMAD Protein Complex Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process I-SMAD Binding Positive Regulation Of Macromolecule Metabolic Process Nucleus BMP Signaling Pathway DNA-templated Transcription Regulation Of Macromolecule Metabolic Process SMAD Protein Signal Transduction Regulation Of Metabolic Process Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Developmental Process Sequence-specific Double-stranded DNA Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Nucleic Acid Metabolic Process Supercoiled DNA Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Negative Regulation Of Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Bubble DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Intracellular Iron Ion Homeostasis Regulation Of Multicellular Organismal Process