RAPSN and MUSK

Number of citations of the paper that reports this interaction (PMID 9136771)
41

Data Source:
HPRD (in vivo)

		RAPSN	MUSK
Gene Name		receptor-associated protein of the synapse	muscle, skeletal, receptor tyrosine kinase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Plasma Membrane Cell Junction Neuromuscular Junction Postsynaptic Membrane	Integral Component Of Plasma Membrane Cell Junction Neuromuscular Junction Receptor Complex Postsynaptic Membrane
	Molecular Function	Zinc Ion Binding Acetylcholine Receptor Binding Ionotropic Glutamate Receptor Binding Protein Anchor	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Synaptic Transmission Synaptic Transmission, Cholinergic Positive Regulation Of Neuron Apoptotic Process Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Neuromuscular Synaptic Transmission Regulation Of Postsynaptic Membrane Organization	Positive Regulation Of Protein Phosphorylation Regulation Of Transcription, DNA-templated Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organismal Development Neuromuscular Junction Development Memory Regulation Of Synaptic Growth At Neuromuscular Junction Positive Regulation Of Gene Expression Peptidyl-tyrosine Phosphorylation Cell Differentiation Extracellular Matrix Organization Positive Regulation Of Neuron Apoptotic Process Protein Autophosphorylation Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Geranylgeranylation
Pathways			ECM proteoglycans
Drugs
Diseases
GWAS			Pulmonary function decline ( 22424883) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Protein-Protein Interactions		6 interactors: CHRNB1 DAG1 GRB2 KHDRBS1 MUSK UBE2Z	4 interactors: COLQ DOK7 RAPSN SYNE1
Entrez ID		5913	4593
HPRD ID		03353	03190
Ensembl ID		ENSG00000165917	ENSG00000030304
Uniprot IDs		Q13702	O15146
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Membrane Organization Nerve Maturation Positive Regulation Of Protein Geranylgeranylation Calcium-dependent Cell-matrix Adhesion Positive Regulation Of RNA Export From Nucleus Response To Organonitrogen Compound Regulation Of Synaptic Growth At Neuromuscular Junction Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure	Synaptic Transmission, Cholinergic Receptor Clustering Neuromuscular Junction Development Protein Localization Positive Regulation Of Neuromuscular Synaptic Transmission Synapse Organization Acetylcholine Catabolic Process In Synaptic Cleft Nuclear Matrix Anchoring At Nuclear Membrane Regulation Of Postsynaptic Membrane Organization Nuclear Matrix Organization Acetylcholine Catabolic Process Cellular Protein Localization Protein Localization To Membrane Skeletal Muscle Acetylcholine-gated Channel Clustering Cytoskeletal Anchoring At Nuclear Membrane Neurotransmitter Catabolic Process Maintenance Of Protein Location In Nucleus Synaptic Transmission Cellular Localization Asymmetric Protein Localization Establishment Of Nucleus Localization Neurotransmitter Metabolic Process Postsynaptic Membrane Organization Positive Regulation Of Protein Tyrosine Kinase Activity Membrane Organization Nucleus Localization Cell-cell Signaling Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Death Golgi Organization
Tagcloud ?			amine butylacetophenone butylxylene centrilobular cosmetics cyp1a cyp2b cyp3a cytochromes dinitro dosed equimolar gavage isozymes ketone microsomes mk musks mx nitroaromatic nitromusk noel observable p450 perfume phenobarbital toiletries trinitro xylene
Tagcloud (Difference) ?			amine butylacetophenone butylxylene centrilobular cosmetics cyp1a cyp2b cyp3a cytochromes dinitro dosed equimolar gavage isozymes ketone microsomes mk musks mx nitroaromatic nitromusk noel observable p450 perfume phenobarbital toiletries trinitro xylene
Tagcloud (Intersection) ?