IL22RA1 and IL22

Number of citations of the paper that reports this interaction (PMID 11035029)
60

Data Source:
HPRD (in vivo)

		IL22RA1	IL22
Gene Name		interleukin 22 receptor, alpha 1	interleukin 22
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Interferon Receptor Activity Interleukin-20 Binding	Cytokine Activity Interleukin-22 Receptor Binding
	Biological Process	Biological_process Cytokine-mediated Signaling Pathway Defense Response To Gram-negative Bacterium	Acute-phase Response Inflammatory Response Cell-cell Signaling Response To Glucocorticoid
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)
Protein-Protein Interactions		2 interactors: IL22 STAT3	3 interactors: IL10RB IL22RA1 IL22RA2
Entrez ID		58985	50616
HPRD ID		16108	05621
Ensembl ID		ENSG00000142677	ENSG00000127318
Uniprot IDs		Q8N6P7	Q9GZX6
PDB IDs		3DGC 3DLQ	1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S
Enriched GO Terms of Interacting Partners?		Acute-phase Response Acute Inflammatory Response Inflammatory Response Response To Steroid Hormone Negative Regulation Of Glycolytic Process Radial Glial Cell Differentiation Interleukin-6-mediated Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Response To Hormone JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Temperature Homeostasis Growth Hormone Receptor Signaling Pathway Regulation Of Glycolytic Process Cellular Response To Growth Hormone Stimulus Cellular Response To Interleukin-6 Positive Regulation Of Notch Signaling Pathway Eating Behavior Negative Regulation Of Neuron Migration Response To Interleukin-6 Defense Response Response To Growth Hormone Astrocyte Differentiation Eye Photoreceptor Cell Differentiation JAK-STAT Cascade Regulation Of Neuron Migration Regulation Of Notch Signaling Pathway Somatic Stem Cell Maintenance Regulation Of Generation Of Precursor Metabolites And Energy	Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cellular Response To Organic Substance Response To Organic Substance Cell Surface Receptor Signaling Pathway Response To Other Organism Response To Biotic Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Defense Response To Gram-negative Bacterium Defense Response Signal Transduction Regulation Of JAK-STAT Cascade Negative Regulation Of Inflammatory Response Signaling Cell Communication Response To External Stimulus Defense Response To Virus Cellular Response To Stimulus
Tagcloud ?			aucs bead constituted crp discriminated discriminative erythrocyte follows ifngamma il10 il12p70 il13 il17 il1beta il4 il5 il6 il9 immunoassay inverse multiplex object pct procalcitonin sedimentation sepsis septic sirs
Tagcloud (Difference) ?			aucs bead constituted crp discriminated discriminative erythrocyte follows ifngamma il10 il12p70 il13 il17 il1beta il4 il5 il6 il9 immunoassay inverse multiplex object pct procalcitonin sedimentation sepsis septic sirs
Tagcloud (Intersection) ?